SCHEMBL3282907

SCHEMBL3282907

Clc1ccc(-c2ccc(Sc3ccc(-c4ccc(Cl)cc4)cc3)cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.56
MAOB P27338 3/20 0.56
CYP1A2 P05177 1/20 0.52
MEN1 O00255 1/20 0.50
KMT2A Q03164 1/20 0.50
CTRC Q99895 1/20 0.48
LMNA P02545 2/20 0.47
CYP2A6 P11509 1/20 0.47
AHR P35869 2/20 0.46
CHRNA7 P36544 1/20 0.45
L3MBTL1 Q9Y468 2/20 0.45
HAO1 Q9UJM8 1/20 0.45
NPSR1 Q6W5P4 2/20 0.44
NPC1 O15118 1/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
RAB9A P51151 1/20 0.44
RHEB Q15382 1/20 0.42
ALOX5 P09917 1/20 0.42
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9474836 1.00 MAOA (0.56) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL9475224 0.91 MAOA (0.64) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL481976 0.91 MAOA (0.64) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL9476350 0.91 MAOA (0.64) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL10534271 0.90 CYP1A2 (0.71) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL6546576 0.88 MAOA (0.61) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL6546581 0.88 MAOA (0.61) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL28432241 0.86 MAOA (0.50) MAOAMAOBCYP1A2MEN1KMT2A
Biphenyl SCHEMBL17985318 0.83 CYP1A2 (0.61) MAOAMAOBCYP1A2MEN1KMT2A
SCHEMBL944439 0.82 CYP1A2 (0.52) MAOAMAOBCYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469604-B2 Method of manufacturing sulfonium salt TOYO GOSEI CO., LTD. (JP) 2016-10-18 US claimed
US-9469604-B2 Method of manufacturing sulfonium salt TOYO GOSEI CO., LTD. (JP) 2016-10-18 US disclosed
US-20160068477-A1 METHOD OF MANUFACTURING SULTONIUM SALT TOYO GOSEI CO., LTD. (JP) 2016-03-10 US disclosed
US-7709548-B2 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SAN-APRO LIMITED (JP) 2010-05-04 US disclosed
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE SAN-APRO LIMITED (JP) 2009-06-25 US disclosed
US-7442459-B2 Solid electrolyte, membrane and electrode assembly, and fuel cell FUJIFILM CORPORATION (JP) 2008-10-28 US disclosed
US-20080249270-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product DATE MASASHI 2008-10-09 US disclosed
EP-1953139-A1 METHOD FOR PRODUCING FLUORINATED SULFONIUM ALKYLFLUOROPHOSPHATE San-Apro Ltd. (JP) 2008-08-06 EP disclosed
EP-1350789-B1 PROCESS FOR PRODUCING SULFONIUM SALT SAN APRO LTD (JP) 2008-06-25 EP disclosed
US-20080108720-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product DATE MASASHI 2008-05-08 US disclosed
EP-1640363-B1 PROCESS FOR PRODUCTION OF MONOSULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, CURABLE COMPOSITIONS, AND PRODUCTS OF CURING SAN APRO LTD (JP) 2008-01-16 EP disclosed
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing SAN-APRO LIMITED (JP) 2006-11-02 US disclosed
US-7060858-B2 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2006-06-13 US disclosed
EP-1640363-A1 PROCESS FOR PRODUCTION OF MONOSULFONIUM SALTS, CATIONIC POLYMERIZATION INITIATORS, CURABLE COMPOSITIONS, AND PRODUCTS OF CURING San-Apro Limited (JP) 2006-03-29 EP disclosed
US-20040030158-A1 Method for manufacturing sulfonium salts SAN-APRO LIMITED (JP) 2004-02-12 US disclosed
EP-1350789-A1 PROCESS FOR PRODUCING SULFONIUM SALT San-Apro Limited (JP) 2003-10-08 EP disclosed
US-4248795-A BY OXIDATION OF THE CORRESPONDING SULFIDE WITH AN AQUEOUS PERACID SOLUTION UNION CARBIDE CORPORATION (US) 1981-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060247401-A1 Process for production of monosulfonium salts, cationic polymerization initiators, curable compositions, and products of curing RPS6, SPIN4, SRM MAOA 3278/4885MAOB 3263/4885CYP1A2 3904/4885
US-20040030158-A1 Method for manufacturing sulfonium salts MLX, STS, SULT1A1 MAOA 831/4885MAOB 851/4885CYP1A2 80/4885
US-20090163723-A1 METHOD FOR PRODUCING SULFONIUM FLUORINATED ALKYLFLUOROPHOSPHATE ARSA, SCO2, DOHH MAOA 2326/4885MAOB 2031/4885CYP1A2 583/4885
US-20080108720-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SPIN4, RPS6, SRM MAOA 3349/4885MAOB 3254/4885CYP1A2 4180/4885
US-20080249270-A1 Method for manufacturing monosulfonium salt, cationic polymerization initiator, curable composition, and cured product SPIN4, RPS6, SRM MAOA 3349/4885MAOB 3254/4885CYP1A2 4180/4885
US-20160068477-A1 METHOD OF MANUFACTURING SULTONIUM SALT STS, SULT1A1, ARSA MAOA 4760/4885MAOB 4672/4885CYP1A2 1424/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.