Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.83 |
| ▸ | PPARG | P37231 | 16/20 | 0.83 |
| ▸ | PPARD | Q03181 | 4/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5342984 | 1.00 | PPARA (0.83) | PPARAPPARGPPARDPGRADORA3 | |
| SCHEMBL6003718 | 0.93 | PPARG (0.72) | PPARAPPARGPPARD | |
| SCHEMBL6002523 | 0.93 | PPARG (0.81) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL4822459 | 0.91 | PPARA (1.00) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL29369224 | 0.91 | PPARA (1.00) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL676872 | 0.91 | PPARA (1.00) | PPARAPPARGPPARD | |
| Ragaglitazar SCHEMBL682732 | 0.91 | PPARA (1.00) | PPARAPPARGPPARD | |
| SCHEMBL6003707 | 0.91 | PPARG (0.69) | PPARAPPARGPPARD | |
| SCHEMBL7246044 | 0.90 | PPARG (0.74) | PPARAPPARGPPARD | |
| SCHEMBL21621206 | 0.88 | PPARG (0.80) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414128-B2 | Crystalline R-guanidines, Arginine or (L)-Arginine (2S)-2-Ethoxy-3-{4-[2-(10H -phenoxazin-10-yl)ethoxy]phenyl}propanoate | DR. REDDY'S LABORATORIES, LIMITED (IN) | 2008-08-19 | — | — | US | disclosed |
| US-20050159600-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | DR. REDDY'S LABORATORIES, INC. | 2005-07-21 | — | — | US | disclosed |
| US-20030004341-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | EBDRUP SOREN (DK) | 2003-01-02 | — | — | US | disclosed |
| WO-2000063189-A1 | CRYSTALLINE R- GUANIDINES, ARGININE OR (L) -ARGININE (2S) -2- ETHOXY -3-{4- [2-(10H -PHENOXAZIN -10-YL)ETHOXY]PHENYL}PROPANOATE | NOVO NORDISK A/S (DK) | 2000-10-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050159600-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | PRMT3, ARG1, ARGLU1 | PPARA 530/4885PPARG 769/4885PPARD 569/4885 |
| US-20030004341-A1 | Crystalline R-guanidines, arginine or (L)-arginine (2S)-2-ethoxy-3-{4-[2-(10H-phenoxazin-10-yl)ethoxy]phenyl}propanoate | PRMT3, ARG1, ARGLU1 | PPARA 932/4885PPARG 1181/4885PPARD 835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.