Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 1.00 |
| ▸ | MEN1 | O00255 | 9/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 9/20 | 1.00 |
| ▸ | MAPT | P10636 | 9/20 | 0.85 |
| ▸ | RAB9A | P51151 | 1/20 | 0.78 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | PKM | P14618 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6803445 | 0.81 | CA1 (0.77) | ALDH1A1MEN1KMT2AMAPTGAA | |
| SCHEMBL21416015 | 0.80 | MEN1 (0.66) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL9003269 | 0.79 | MAPT (0.70) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL4823307 | 0.79 | ALDH1A1 (0.65) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL4818387 | 0.79 | MAPT (0.75) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL4823249 | 0.79 | CA2 (0.90) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL4661775 | 0.78 | CA2 (0.76) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL25340071 | 0.77 | MEN1 (0.62) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL11403189 | 0.77 | ALDH1A1 (0.62) | ALDH1A1MEN1KMT2AMAPTPKM | |
| SCHEMBL14061940 | 0.76 | CA2 (0.69) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-7347879-B2 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'Oreál, S.A. (FR) | 2008-03-25 | — | — | US | disclosed |
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | L'OREAL S.A. (FR) | 2006-01-12 | — | — | US | disclosed |
| EP-1568687-A1 | Sulphur-containing secondary para-Phenylenediamines, dying composition containing such para-phenylenediamines and methods using this composition and use | L'OREAL (FR) | 2005-08-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060005321-A1 | Sulfur-containing secondary para-phenylenediamines dye compositions comprising such para-phenylenediamines, processes, and uses thereof | KRT18, CDC73, DSG1 | ALDH1A1 1148/4885MEN1 3813/4885KMT2A 2395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.