Sugi Predict

Sugi Predict / Compounds / SCHEMBL482336

SCHEMBL482336

SCHEMBL482336

O=[N+]([O-])c1ccc(CBr)o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.61
▸ TDP1 Q9NUW8 3/20 0.44
▸ L3MBTL1 Q9Y468 3/20 0.44
▸ KMT2A Q03164 2/20 0.44
▸ KDM4E B2RXH2 1/20 0.44
▸ MEN1 O00255 1/20 0.44
▸ NPC1 O15118 1/20 0.44
▸ MITF O75030 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.44
▸ MAPT P10636 1/20 0.44
▸ XBP1 P17861 1/20 0.44
▸ RAB9A P51151 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ NPSR1 Q6W5P4 1/20 0.44
▸ POLB P06746 3/20 0.41
▸ HTT P42858 2/20 0.39
▸ NFKB1 P19838 1/20 0.39
▸ RECQL P46063 1/20 0.39
▸ BLM P54132 1/20 0.39
▸ NFKB2 Q00653 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27512957 0.84 LMNA (0.58) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2813240 0.81 LMNA (0.63) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2089914 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL6729712 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL5077063 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL2056126 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL1977597 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL4118512 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL5077061 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E
SCHEMBL18459658 0.79 LMNA (0.61) LMNATDP1L3MBTL1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116375643-B Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2025-04-01 — — CN claimed
CN-116375643-A Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2023-07-04 — — CN claimed
CN-115521300-A Double-ratio type fluorescence/photoacoustic probe and preparation method and application thereof 广西师范大学 2022-12-27 — — CN claimed
EP-4743446-A1 NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA Board of Trustees of Michigan State University (US) 2026-05-20 — — EP disclosed
US-12576156-B2 Compound comprising self-immolative group and ligand-drug conjugate comprising same TRIOAR, INC. (KR) 2026-03-17 — — US disclosed
US-20250136574-A1 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS UNIV MISSISSIPPI (US) 2025-05-01 — — US disclosed
EP-4545096-A1 COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME Trioar, Inc. (KR) 2025-04-30 — — EP disclosed
US-20250121072-A1 COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME TRIOAR, INC. (KR) 2025-04-17 — — US disclosed
CN-116375643-B Deaconitine derivative and preparation method and application thereof 中国人民解放军海军军医大学 2025-04-01 — — CN disclosed
CN-119451701-A Compounds comprising self-destructing groups and ligand-drug conjugates comprising the same 特里奥尔株式会社 2025-02-14 — — CN disclosed
WO-2025015066-A1 NITRO-CONTAINING COMPOUNDS THAT KILL MYCOBACTERIA BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) 2025-01-16 — — WO disclosed
US-6030979-A INHIBITS THE STEROL 14-REDUCTASE WHICH CATALYZES THE BIOSYNTHESIS OF CHOLESTEROL FROM LANOSTEROL; ANTICHOLESTEROL AND-LIPEMIC AGENTS HANWHA CORPORATION (CN) 2000-02-29 — — US disclosed
US-6028197-A ENZYME INHIBITORS INHIBITING THE STEROL 14-REDUCTASE WHICH IS INVOLVED IN THE DISTAL PATHWAY OF CHOLESTEROL BIOSYNTHESIS, AND THE USE AS ANTICHOLESTEROL AGENTS OR ANTILIPEMIC AGENTS HANWHA CORPORATION (KR) 2000-02-22 — — US disclosed
EP-0629617-B1 Heteroatom-bearing ligands and metal complexes thereof BRACCO INT BV (NL) 1998-04-29 — — EP disclosed
US-5741912-A DIAGNOSIS, THERAPY BRACCO INTERNATIONAL B.V. 1998-04-21 — — US disclosed
US-5665329-A Heteroatom-bearing ligands and metal complexes thereof BRACCO INTERNATIONAL B.V. 1997-09-09 — — US disclosed
US-5656254-A Polyaza heteroatom-bearing ligands and metal complexes thereof for imaging or radiotherapy BRACCO INTERNATIONAL B.V. 1997-08-12 — — US disclosed
US-5627286-A Heteroatom-bearing ligands and metal complexes thereof BRACCO INTERNATIONAL B.V. 1997-05-06 — — US disclosed
US-5608110-A Heteroatom-bearing ligands and metal complexes thereof BRACCO INTERNATIONAL B.V. 1997-03-04 — — US disclosed
EP-0629617-A1 Heteroatom-bearing ligands and metal complexes thereof BRACCO International B.V. (NL) 1994-12-21 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12576156-B2 Compound comprising self-immolative group and ligand-drug conjugate comprising same SLC7A1, CLTC, MSR1 LMNA 1990/4885TDP1 4191/4885L3MBTL1 142/4885
US-20250121072-A1 COMPOUND COMPRISING SELF-IMMOLATIVE GROUP AND LIGAND-DRUG CONJUGATE COMPRISING SAME CD44, MSN, EPCAM LMNA 3561/4885TDP1 3478/4885L3MBTL1 1566/4885
US-20250136574-A1 SELECTIVE AGENTS TARGETING MYCOBACTERIUM TUBERCULOSIS SLC11A2, FNTB, ABCC1 LMNA 3706/4885TDP1 3919/4885L3MBTL1 1084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.