Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.54 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.54 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.54 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29944901 | 1.00 | LOXL2 (0.61) | LOXL2IDO1SMN1; SMN2NPSR1PIK3CD | |
| SCHEMBL77839 | 0.84 | RAB9A (0.61) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL27769376 | 0.82 | RAB9A (0.59) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL10831817 | 0.82 | RAB9A (0.59) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL780242 | 0.81 | SMN1; SMN2 (0.61) | LOXL2IDO1SMN1; SMN2NPSR1ALDH1A1 | |
| Nitrogen SCHEMBL29238121 | 0.81 | RAB9A (0.58) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2190447 | 0.79 | ALDH1A1 (0.61) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL7409329 | 0.78 | SMN1; SMN2 (0.58) | LOXL2IDO1SMN1; SMN2NPSR1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11236118 | 0.78 | ALDH1A1 (0.59) | SMN1; SMN2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL72699 | 0.76 | GAA (0.72) | SMN1; SMN2NPSR1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398771-A2 | HETEROCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2011-12-28 | — | — | EP | claimed |
| WO-2010096371-A2 | HETEROCYCLIC COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-08-26 | — | — | WO | claimed |
| EP-1034176-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-09-13 | — | — | EP | claimed |
| WO-1999028316-A1 | THIOPHENE-SULFONAMIDE COMPOUNDS | PHARMACIA & UPJOHN S.P.A. (IT) | 1999-06-10 | — | — | WO | claimed |
| JP-7267950-A | — | — | None | — | — | JP | disclosed |
| JP-55000344-A | — | — | None | — | — | JP | disclosed |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2026-03-31 | — | — | US | disclosed |
| US-12545649-B2 | WDR5-MYC inhibitors | VANDERBILT UNIVERSITY (US) | 2026-02-10 | — | — | US | disclosed |
| CN-120136812-A | Compound for targeted degradation of transcription factor KLF5 and application thereof | 昆明医科大学 | 2025-06-13 | — | — | CN | disclosed |
| WO-2025031129-A1 | ARYL UREA DERIVATIVE, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AND USE THEREOF | 沈阳药科大学 | 2025-02-13 | — | — | WO | disclosed |
| CN-114846013-B | Novel aminoaryl derivatives useful as diacylglycerol acyltransferase 2 inhibitors and uses thereof | 株式会社LG化学 | 2024-12-20 | — | — | CN | disclosed |
| CN-118359602-A | Aryl urea derivative and application thereof | 沈阳药科大学 | 2024-07-19 | — | — | CN | disclosed |
| US-5120872-A | Textile dyeing | CIBA-GEIGY CORPORATION (US) | 1992-06-09 | — | — | US | disclosed |
| US-4994563-A | Dyeing, printing cellulose, silk, wool, synthetic polyamides; colorfastness | CIBA-GEIGY CORPORATION (US) | 1991-02-19 | — | — | US | disclosed |
| EP-0349486-A2 | Azo dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1990-01-03 | — | — | EP | disclosed |
| US-4236007-A | YELLOW SHADES ON POLYESTERS | CIBA-GEIGY AKTIENGESELLSCHAFT (CH) | 1980-11-25 | — | — | US | disclosed |
| JP-S55344-A | 2-NITROSOIMINOBENZTHIAZOLINE DERIVATIVE | IWAKI SEIYAKU KK | 1980-01-05 | — | — | JP | disclosed |
| US-4148805-A | POLYESTERS, RED, YELLLOW | CIBA-GEIGY AG (CH) | 1979-04-10 | — | — | US | disclosed |
| US-4057638-A | Benzothiazole allophanate fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-11-08 | — | — | US | disclosed |
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545649-B2 | WDR5-MYC inhibitors | MYC, MYCBP, WDR1 | LOXL2 3082/4885IDO1 4396/4885SMN1; SMN2 3142/4885 |
| US-12590071-B2 | Hydrazone derivative in which terminal amine group is substituted with aryl group or heteroaryl group, and use thereof | ABL1, TH, CYP3A43 | LOXL2 1394/4885IDO1 11/4885SMN1; SMN2 4531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.