SCHEMBL2190447

SCHEMBL2190447

Nc1ccc2sc(N)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
MAPT P10636 4/20 0.61
RAB9A P51151 4/20 0.61
NPC1 O15118 4/20 0.61
GFER P55789 3/20 0.61
KDM4E B2RXH2 3/20 0.61
KMT2A Q03164 3/20 0.61
GAA P10253 2/20 0.61
POLB P06746 2/20 0.61
MEN1 O00255 2/20 0.61
NFKB1 P19838 1/20 0.61
NFKB2 Q00653 1/20 0.61
RELA Q04206 1/20 0.61
PIK3CA P42336 2/20 0.58
PIK3CD O00329 1/20 0.58
PIK3CB P42338 1/20 0.58
PIK3CG P48736 1/20 0.58
SMN1; SMN2 Q16637 4/20 0.53
TP53 P04637 2/20 0.53
CYP3A4 P08684 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11236118 0.98 ALDH1A1 (0.59) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL334946 0.83 RAB9A (0.66) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL22130141 0.81 MAPT (0.59) ALDH1A1MAPTRAB9ANPC1GFER
Hydrochloric Acid SCHEMBL3851081 0.81 RAB9A (0.63) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL72699 0.79 GAA (0.72) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL12262 0.79 MAPT (0.72) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL21983970 0.79 PIK3CA (0.54) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL13244648 0.79 PIK3CA (0.54) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL30015562 0.79 PIK3CA (0.54) ALDH1A1MAPTRAB9ANPC1GFER
SCHEMBL482340 0.79 LOXL2 (0.61) ALDH1A1MAPTRAB9ANPC1GFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN claimed
CN-117924615-A Preparation method of organic silicon resin flame retardant for polycarbonate material 衢州学院 2024-04-26 CN claimed
WO-2024046225-A1 ESTER TYPE PHOTOSENSITIVE POLYIMIDE COMPOSITE MATERIAL, PREPARATION METHOD AND SEMICONDUCTOR APPARATUS 深圳先进电子材料国际创新研究院 2024-03-07 WO claimed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN claimed
CN-115509088-A Ester type photosensitive polyimide composite material, preparation method and semiconductor device 深圳先进电子材料国际创新研究院 2022-12-23 CN claimed
CN-114805805-A Polyimide with high bonding strength and preparation method and application thereof 中国科学院深圳先进技术研究院 2022-07-29 CN claimed
CN-110183727-B Benzothiazole nitrogen phosphorus sulfur ternary synergistic flame retardant containing double DOPO units, and preparation method and application thereof 三峡大学 2021-03-23 CN claimed
CN-110183727-A Benzothiazole nitrogen phosphorus sulphur synergistic flame retardant containing double DOPO units, preparation method and applications 三峡大学 2019-08-30 CN claimed
US-4321363-A Adsorbent for urokinase containing agarose NIPPON SODA COMPANY LIMITED (JP) 1982-03-23 US claimed
WO-2025064853-A1 RIPK3 INHIBITORS AND METHODS OF USE Momentum Therapeutics, Inc. (US) 2025-03-27 WO disclosed
US-20250092031-A1 RIPK3 INHIBITORS AND METHODS OF USE INTEGRAL BIOSCIENCES PVT. LTD. (IN) 2025-03-20 US disclosed
CN-118126325-A Low-temperature-cured alkali-soluble photosensitive resin and preparation method thereof 深圳先进电子材料国际创新研究院 2024-06-04 CN disclosed
CN-117924615-A Preparation method of organic silicon resin flame retardant for polycarbonate material 衢州学院 2024-04-26 CN disclosed
CN-114805805-B Polyimide with high adhesive strength and preparation method and application thereof 深圳先进电子材料国际创新研究院 2023-12-19 CN disclosed
EP-0194413-A2 Printed circuit element with a cover sheet containing polyimide Akzo Patente GmbH (DE) 1986-09-17 EP disclosed
EP-0167020-A2 Flexible polyimide multilayer laminate Akzo Patente GmbH (DE) 1986-01-08 EP disclosed
US-4522880-A EXTRUSION ON SUBSTRATE, THEN CURING AKZONA INCORPORATED (US) 1985-06-11 US disclosed
EP-0116297-A2 Polyimide laminate with peel-resistance and method of manufacturing it Akzo GmbH (DE) 1984-08-22 EP disclosed
US-4321363-A Adsorbent for urokinase containing agarose NIPPON SODA COMPANY LIMITED (JP) 1982-03-23 US disclosed
US-3957860-A SULFAMIC ACID CIBA-GEIGY AG (CH) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250092031-A1 RIPK3 INHIBITORS AND METHODS OF USE RIPK3, RIPK1, RIPK2 ALDH1A1 4773/4885MAPT 2485/4885RAB9A 2206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.