Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 3/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2881296 | 0.96 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL2881389 | 0.96 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL2877951 | 0.96 | TSHR (0.57) | TSHRTHRBLMNASLC22A1DNM1 | |
| SCHEMBL1548938 | 0.88 | TSHR (0.46) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| Hexane SCHEMBL27926505 | 0.74 | TSHR (0.70) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| Hexane SCHEMBL44009 | 0.74 | — | — | |
| Hexane SCHEMBL183946 | 0.74 | — | — | |
| Hexane SCHEMBL1706108 | 0.74 | TSHR (0.70) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| Hexane SCHEMBL357364 | 0.73 | TSHR (0.88) | TSHRTHRBLMNASLC22A1SLC22A2 | |
| Hexane SCHEMBL8705498 | 0.73 | TSHR (0.88) | TSHRTHRBLMNASLC22A1SLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11998621-B2 | Transparent, fracture-tough polymerization resins for the production of dental shaped bodies | IVOCLAR VIVADENT AG (LI) | 2024-06-04 | — | — | US | claimed |
| CN-111228124-B | Rapidly curing and low shrinkage stress photopolymerizable dental composites | 义获嘉伟瓦登特公司 | 2024-04-09 | — | — | CN | claimed |
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | IVOCLAR VIVADENT AG (LI) | 2023-08-24 | — | — | US | claimed |
| EP-3632941-B1 | RESIN COMPOSITION | CUBICURE GMBH (AT) | 2023-08-23 | — | — | EP | claimed |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | IVOCLAR VIVADENT AG (LI) | 2023-06-13 | — | — | US | claimed |
| CN-115300400-A | Transparent, fracture-tough polymeric resins for the production of dental molded bodies | 义获嘉伟瓦登特公司 | 2022-11-08 | — | — | CN | claimed |
| CN-111228124-A | Rapid curing and low shrinkage stress photopolymerizable dental composites | 义获嘉伟瓦登特公司 | 2020-06-05 | — | — | CN | claimed |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | IVOCLAR VIVADENT AG (LI) | 2020-05-28 | — | — | US | claimed |
| US-12043683-B2 | Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives | IVOCLAR VIVADENT AG (LI) | 2024-07-23 | — | — | US | disclosed |
| CN-113288817-B | Dental materials based on cyclizable polymeric crosslinkers | 义获嘉伟瓦登特公司 | 2024-06-14 | — | — | CN | disclosed |
| US-11998621-B2 | Transparent, fracture-tough polymerization resins for the production of dental shaped bodies | IVOCLAR VIVADENT AG (LI) | 2024-06-04 | — | — | US | disclosed |
| US-20240164996-A1 | DENTAL MATERIAL FOR THE PREPARATION OF FULL OR PARTIAL DENTAL PROSTHESES | IVOCLAR VIVADENT AG (LI) | 2024-05-23 | — | — | US | disclosed |
| US-20240158614-A1 | STORAGE STABLE SELF-ADHESIVE COMPOSITE CEMENTS WITH GOOD TRANSPARENCY AND GOOD RADIOPACITY | IVOCLAR VIVADENT AG (LI) | 2024-05-16 | — | — | US | disclosed |
| EP-4368167-A1 | DENTAL MATERIAL FOR PRODUCING FULL OR PARTIAL DENTAL PROSTHESES | Ivoclar Vivadent AG (LI) | 2024-05-15 | — | — | EP | disclosed |
| WO-2001085138-A2 | PARTICULATE ENCAPSULATION OF LIQUID BEADS | AVEKA, INC. (US) | 2001-11-15 | — | — | WO | disclosed |
| US-6139613-A | Multilayer pigments and their manufacture | AVEKA, INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-1017746-A1 | HYDROPHILIC MATERIALS AND THEIR METHOD OF PREPARATION | SUNSMART, INC. (US) | 2000-07-12 | — | — | EP | disclosed |
| US-6045650-A | A LIQUID COATING OF AN OXIDIZABLE MATERIAL CONTAINING AT LEAST ONE ELEMENT OTHER THAN CARBON, HYDROGEN, OXYGEN AND NITROGEN IS APPLIED ONTO THE SURFACE OF A SUBSTRATE, OXIDIZING THE OXIDIZABLE MATERIAL TO FORM AN OXIDE COATING | SUNSMART, INC. (US) | 2000-04-04 | — | — | US | disclosed |
| US-5962082-A | Process for applying liquid coatings to solid particulate substrates | AVEKA, INC. (US) | 1999-10-05 | — | — | US | disclosed |
| WO-1999014276-A1 | HYDROPHILIC MATERIALS AND THEIR METHOD OF PREPARATION | SUNSMART, INC. (US) | 1999-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240164996-A1 | DENTAL MATERIAL FOR THE PREPARATION OF FULL OR PARTIAL DENTAL PROSTHESES | FHIT, MMAB, HBB | TSHR 2548/4885THRB 966/4885LMNA 1758/4885 |
| US-20230265220-A1 | Photopolymerizable Dental Composites With Rapid Curing And Low Shrinkage Stress | MMAB, ALAD, SULT1E1 | TSHR 3592/4885THRB 1324/4885LMNA 1738/4885 |
| US-11998621-B2 | Transparent, fracture-tough polymerization resins for the production of dental shaped bodies | MMAB, VCL, BOLA2; BOLA2B | TSHR 1668/4885THRB 100/4885LMNA 1795/4885 |
| US-11673980-B2 | Photopolymerizable dental composites with rapid curing and low shrinkage stress | MMAB, ALAD, SULT1E1 | TSHR 3592/4885THRB 1324/4885LMNA 1738/4885 |
| US-20200165363-A1 | PHOTOPOLYMERIZABLE DENTAL COMPOSITES WITH RAPID CURING AND LOW SHRINKAGE STRESS | MMAB, ALAD, SULT1E1 | TSHR 3592/4885THRB 1324/4885LMNA 1738/4885 |
| US-12043683-B2 | Dental materials based on redox systems with oligomeric cumene hydroperoxide derivatives | CBR3, NR1H3, NR1I3 | TSHR 1220/4885THRB 533/4885LMNA 3873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.