Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.31 |
| ▸ | PPARG | P37231 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5200688 | 0.84 | PPARA (0.42) | ICMTPPARGTSHR | |
| SCHEMBL4824300 | 0.78 | ICMT (0.38) | ICMTNPSR1RXFP1PPARGMEN1 | |
| SCHEMBL3871885 | 0.72 | ACE (0.44) | ICMTPPARGC3AR1 | |
| SCHEMBL4825384 | 0.72 | ACE (0.44) | ICMTPPARGC3AR1 | |
| SCHEMBL5780394 | 0.70 | ALDH1A1 (0.35) | PPARGMEN1TSHRKMT2AALDH1A1 | |
| SCHEMBL5262506 | 0.69 | EPHX2 (0.33) | ICMTPPARGMEN1KMT2A | |
| SCHEMBL5783679 | 0.68 | PPARA (0.41) | ICMTPPARGMEN1TSHRKMT2A | |
| SCHEMBL5764439 | 0.68 | MAPT (0.33) | MAPTALDH1A1 | |
| SCHEMBL4824631 | 0.68 | PPARA (0.42) | PPARGMEN1KMT2APOLB | |
| SCHEMBL5781491 | 0.67 | ACE (0.37) | ICMTPPARGMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358248-B2 | Substituted amino carboxylic acids | THE INSTITUTE FOR PHARMACEUTICAL DISCOVERY LLC (US) | 2008-04-15 | — | — | US | claimed |