Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5744684 | 0.74 | ALOX5 (0.32) | MAPTALOX5 | |
| SCHEMBL5200688 | 0.69 | PPARA (0.42) | — | |
| SCHEMBL5262506 | 0.69 | EPHX2 (0.33) | — | |
| SCHEMBL4824304 | 0.68 | ICMT (0.36) | MAPTALDH1A1 | |
| SCHEMBL4275190 | 0.66 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL4275188 | 0.66 | ALOX5 (0.43) | ALOX5 | |
| SCHEMBL5767369 | 0.64 | MMP12 (0.36) | MAPTALOX5ALDH1A1 | |
| SCHEMBL5260689 | 0.61 | HPGD (0.39) | MAPTALOX5ALDH1A1HPGD | |
| SCHEMBL5767136 | 0.60 | PTPN1 (0.33) | MAPT | |
| SCHEMBL24839766 | 0.58 | ALOX5 (0.31) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006525329-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | disclosed |