Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 6/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824944 | 0.88 | HSD17B10 (0.42) | KDM4EALDH1A1HPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL4598783 | 0.77 | HDAC1 (0.47) | CACNA1GCACNA1HCACNA1BKDM4EALDH1A1 | |
| SCHEMBL4825167 | 0.74 | CHRNA7 (0.40) | KCNH2 | |
| SCHEMBL4817697 | 0.73 | HPGD (0.57) | KDM4EHPGDSMN1; SMN2P2RX7 | |
| SCHEMBL4825556 | 0.71 | HPGD (0.44) | CACNA1GCACNA1HCACNA1BKDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL7759993 | 0.66 | F2 (0.64) | ALDH1A1HPGDHSD17B10SMN1; SMN2F2 | |
| Hydrochloric Acid SCHEMBL7759997 | 0.66 | F2 (0.64) | ALDH1A1HPGDHSD17B10SMN1; SMN2F2 | |
| Hydrochloric Acid SCHEMBL7759991 | 0.66 | F2 (0.64) | ALDH1A1HPGDHSD17B10SMN1; SMN2F2 | |
| SCHEMBL4598779 | 0.65 | KDM4E (0.47) | KDM4EALDH1A1HPGDHSD17B10F2 | |
| SCHEMBL4206586 | 0.65 | ADRA2A (0.47) | KDM4ESMN1; SMN2ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032484-A1 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC | 2007-02-08 | — | — | US | claimed |
| US-7358373-B2 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070032484-A1 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032484-A1 | Cathepsin K inhibitors | CTSK, CTSS, CTSF | CACNA1G 1217/4885CACNA1H 1350/4885CACNA1B 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.