SCHEMBL482524

SCHEMBL482524

CN(C(=O)c1ccccc1)c1[c]cccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 1/20 0.45
HSD11B1 P28845 1/20 0.42
RAB9A P51151 3/20 0.42
NR1H3 Q13133 2/20 0.42
NPC1 O15118 2/20 0.42
NR1H2 P55055 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
CASP3 P42574 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
HTT P42858 1/20 0.41
EGFR P00533 1/20 0.39
ERBB2 P04626 1/20 0.39
HPGD P15428 2/20 0.39
ALDH1A1 P00352 1/20 0.39
GRM1 Q13255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16294301 0.83 RAB9A (0.36) KMT2AKDM4ERAB9ANPC1HPGD
SCHEMBL7647045 0.81 CES1 (0.38) KMT2AKDM4EHSD11B1RAB9ASMN1; SMN2
SCHEMBL6796747 0.80 HPGD (0.40) KMT2AKDM4EHSD11B1RAB9ALMNA
SCHEMBL95841 0.79 ALDH1A1 (0.39) KMT2AKDM4ERAB9ANPC1TP53
SCHEMBL4149882 0.79 CES1 (0.35) KMT2AKDM4EHSD11B1RAB9ANR1H3
SCHEMBL4289334 0.79 TSHR (0.38) KDM4EHSD11B1RAB9ASMN1; SMN2HTT
SCHEMBL1416233 0.78 ALOX5 (0.34) KMT2ATP53SMN1; SMN2ALDH1A1RECQL
SCHEMBL26597591 0.78 NR1H3 (0.43) KMT2AKDM4EHSD11B1RAB9ANR1H3
SCHEMBL3790835 0.78 CYP2C9 (0.47) KMT2ARAB9ANPC1LMNACASP3
SCHEMBL6797312 0.77 NR3C2 (0.44) KMT2AKDM4ERAB9ANPC1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3353146-B1 SYNTHESIS OF SUBSTITUTED AMIDOBENZOATE COMPOUNDS, THE COMPOUNDS OBTAINED AND THE USE THEREOF AS PHTHALATE FREE INTERNAL ELECTRON DONOR FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-10-25 EP claimed
US-4514490-A COLORFASTNESS; COUPLER WITH METHYLENEDIOAY BENZENE GROUP FUJI PHOTO FILM CO., LTD. (JP) 1985-04-30 US claimed
US-4336325-A CONTAING A MAGENTA COLOR-FORMING COUPLER WHICH PREVENTS YELLOW STAIN FUJI PHOTO FILM CO., LTD. (JP) 1982-06-22 US claimed
US-4163670-A PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1979-08-07 US claimed
CN-110446739-B Fluoroacetophenone-containing derivative, fluorine-containing additive, curable composition containing the same, and cured product thereof DIC株式会社 2022-01-11 CN disclosed
US-10961405-B2 Fluorine-containing acetophenone derivative, fluroine based additive, curable composition including same, and cured product thereof DIC CORPORATION (JP) 2021-03-30 US disclosed
CN-111954849-A Photosensitive resin composition, cured product, insulating material, resin material for solder resist, and resist member DIC株式会社 2020-11-17 CN disclosed
EP-1657286-B1 Radiation curable ink jet ink, comprising a polymerisation initiation sensitising dye FUJIFILM CORP (JP) 2018-07-04 EP disclosed
US-9957402-B2 Compound, active energy ray curable composition, cured article thereof, printing ink, and inkjet recording ink DIC CORPORATION (JP) 2018-05-01 US disclosed
EP-1859954-B2 Planographic printing plate precursor and stack thereof FUJIFILM CORP (JP) 2017-11-08 EP disclosed
EP-2042921-B1 Pigment dispersion composition, photocurable composition and color filter FUJIFILM CORP (JP) 2017-10-25 EP disclosed
EP-2006738-B1 Lithographic printing plate precursor FUJIFILM CORP (JP) 2017-09-06 EP disclosed
US-4514490-A COLORFASTNESS; COUPLER WITH METHYLENEDIOAY BENZENE GROUP FUJI PHOTO FILM CO., LTD. (JP) 1985-04-30 US disclosed
US-4336325-A CONTAING A MAGENTA COLOR-FORMING COUPLER WHICH PREVENTS YELLOW STAIN FUJI PHOTO FILM CO., LTD. (JP) 1982-06-22 US disclosed
US-4297440-A CONTAINING A 3-ANILINO-5-PYRAZOLONE MAGENTA COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-10-27 US disclosed
US-4199361-A 3-ANILINO-5-PYRAZOLONE MAGENTA COLOR-FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-04-22 US disclosed
US-4163670-A PYRAZOLONE COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 1979-08-07 US disclosed
US-4123281-A Photographic silver halide color material containing fast-acting hardener and 2-pyrazolin-5-one coupler precursors AGFA-GEVAERT N.V. (BE) 1978-10-31 US disclosed
US-4105452-A HYDROQUINONE DERIVATIVE OR PRECURSOR SUBSTITUTED WITH A HETEROCYCLIC THIO AND A ALIPHATIC OR ARYL THIO GROUP FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US disclosed
US-3935015-A Silver halide color photographic materials containing 3-anilino-5-pyrazolane couplers FUJI PHOTO FILM CO., LTD. (JA) 1976-01-27 US disclosed