Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17321082 | 0.79 | L3MBTL1 (0.64) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR | |
| SCHEMBL482524 | 0.78 | KMT2A (0.45) | LMNAMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6409033 | 0.74 | CYP2C9 (0.66) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR | |
| SCHEMBL30486023 | 0.73 | TSHR (0.63) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR | |
| SCHEMBL1436095 | 0.73 | TSHR (0.63) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR | |
| SCHEMBL17035531 | 0.72 | CYP2C9 (0.58) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR | |
| SCHEMBL5015216 | 0.72 | KDM4E (0.41) | CYP1A2TSHRL3MBTL1MAPTLMNA | |
| SCHEMBL2535686 | 0.71 | TSHR (0.42) | TSHRL3MBTL1BCHEACHEMAPT | |
| SCHEMBL1416233 | 0.71 | ALOX5 (0.34) | CYP2C19CYP3A4TSHRL3MBTL1MAPT | |
| SCHEMBL14388233 | 0.70 | CYP2C9 (0.63) | CYP2C9CYP2C19CYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010086366-A1 | 4-ARYL-BUTANE-1,3-DIAMIDES | NOVARTIS AG (CH) | 2010-08-05 | — | — | WO | disclosed |