Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193439 | 1.00 | CTSS (0.43) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL4823772 | 0.80 | CTSS (0.50) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL4823757 | 0.78 | CTSS (0.50) | CTSSCYP3A4CYP2C9 | |
| SCHEMBL5254819 | 0.78 | CTSS (0.42) | CTSS | |
| SCHEMBL5254825 | 0.78 | CTSS (0.42) | CTSS | |
| SCHEMBL14565675 | 0.77 | CHRNA7 (0.43) | — | |
| SCHEMBL6752338 | 0.76 | CHRNA7 (0.42) | — | |
| SCHEMBL6752322 | 0.75 | CTSS (0.43) | CTSS | |
| SCHEMBL4825318 | 0.75 | CNR2 (0.44) | CYP2C9 | |
| SCHEMBL6752320 | 0.75 | GHSR (0.43) | CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7358373-B2 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC (US) | 2008-04-15 | — | — | US | disclosed |
| US-20070032484-A1 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC | 2007-02-08 | — | — | US | disclosed |
| US-20070032484-A1 | Cathepsin K inhibitors | ROCHE PALO ALTO LLC | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032484-A1 | Cathepsin K inhibitors | CTSK, CTSS, CTSF | CTSS 2/4885CYP3A4 1911/4885CYP2C9 1781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.