Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | TDO2 | P48775 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL482570 | 0.75 | SMN1; SMN2 (0.64) | SMN1; SMN2ELANEPOLBKDM4EALDH1A1 | |
| SCHEMBL482140 | 0.74 | SMN1; SMN2 (1.00) | SMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9593802 | 0.67 | KMT2A (0.48) | ELANEPOLBKDM4ETP53CA2 | |
| SCHEMBL19120983 | 0.67 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBALDH1A1NPC1NOTUM | |
| SCHEMBL6135830 | 0.66 | MGLL (0.68) | ELANEPOLBPKMALDH1A1 | |
| SCHEMBL7401028 | 0.66 | CYP19A1 (0.40) | ELANEPOLBKDM4ETP53PKM | |
| SCHEMBL12672906 | 0.64 | ELANE (0.44) | SMN1; SMN2ELANEPOLBKDM4ETP53 | |
| SCHEMBL85902 | 0.64 | HTR1A (0.46) | ELANEPOLBPKMCYP19A1PGR | |
| SCHEMBL45942 | 0.64 | CA2 (0.69) | CA2ALDH1A1CYP2A6CA12CA3 | |
| SCHEMBL2503454 | 0.64 | CA2 (0.69) | CA2ALDH1A1CYP2A6CA12CA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116003322-B | Pyrazole ether compound as well as preparation method and application thereof | 南通泰禾化工股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-116003322-A | Pyrazole ether compound as well as preparation method and application thereof | 南通泰禾化工股份有限公司 | 2023-04-25 | — | — | CN | disclosed |