Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 11/20 | 0.44 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4058210 | 0.84 | HSD17B10 (0.45) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL19413462 | 0.84 | ADORA2A (0.49) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL4057372 | 0.81 | PNP (0.41) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL6528880 | 0.78 | HSD17B10 (0.41) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL4364146 | 0.76 | BLM (0.39) | AKR1B1HSD17B10PNPMEN1ALDH1A1 | |
| SCHEMBL9818039 | 0.74 | PNP (0.45) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL25547 | 0.74 | GDA (0.49) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL28168452 | 0.74 | HSD17B10 (0.37) | AKR1B1HPGDHSD17B10PNPKDM4E | |
| SCHEMBL20472443 | 0.73 | AKR1B1 (0.44) | AKR1B1HPGDHSD17B10PNPALDH1A1 | |
| SCHEMBL455760 | 0.73 | HPGD (0.41) | HPGDHSD17B10PNPKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2028272-B1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORP (JP) | 2014-01-08 | — | — | EP | disclosed |
| US-8129115-B2 | Method of modifying nucleotide chain | PANASONIC CORPORATION (JP) | 2012-03-06 | — | — | US | disclosed |
| US-20100291637-A1 | METHOD FOR MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORPORATION (JP) | 2010-11-18 | — | — | US | disclosed |
| US-20100015670-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORPORATION (JP) | 2010-01-21 | — | — | US | disclosed |
| EP-1647592-B1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | PANASONIC CORP (JP) | 2009-03-11 | — | — | EP | disclosed |
| EP-2028272-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | Panasonic Corporation (JP) | 2009-02-25 | — | — | EP | disclosed |
| US-20070077629-A1 | Method for modifying nucleotide chain | PANASONIC CORPORATION (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1647592-A1 | METHOD OF MODIFYING NUCLEOTIDE CHAIN | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 2006-04-19 | — | — | EP | disclosed |