Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.34 |
| ▸ | HTR2A | P28223 | 13/20 | 0.34 |
| ▸ | HTR2C | P28335 | 10/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4835449 | 0.80 | KDM4E (0.42) | KDM4ETP53CD274SLC6A4HTR2A | |
| SCHEMBL4826581 | 0.80 | NOS3 (0.33) | KDM4ETP53SLC6A4HTR2AHTR2C | |
| SCHEMBL26262569 | 0.77 | NOS3 (0.41) | KDM4ETP53CD274 | |
| SCHEMBL4837374 | 0.73 | KDM4E (0.37) | KDM4ETP53SLC6A4HTR2AHTR2C | |
| SCHEMBL24270155 | 0.72 | KDM4E (0.44) | KDM4ETP53CD274 | |
| SCHEMBL2859978 | 0.71 | — | — | |
| SCHEMBL4835923 | 0.69 | KDM4E (0.33) | KDM4ETP53SLC6A4HTR2AHTR2C | |
| SCHEMBL12065872 | 0.69 | KDM4E (0.34) | KDM4ETP53 | |
| SCHEMBL4832258 | 0.69 | KDM4E (0.39) | KDM4E | |
| SCHEMBL12536038 | 0.68 | NPSR1 (0.41) | KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442692-B2 | Indanyl-piperazine compounds | LES LABORATOIRES SERVIER (FR) | 2008-10-28 | — | — | US | disclosed |
| WO-2006103342-A9 | INDANYL-PIPERAZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | SERVIER LAB (FR) | 2007-10-25 | — | — | WO | disclosed |
| EP-1707564-B1 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2007-09-12 | — | — | EP | disclosed |
| US-20060223830-A1 | Indanyl-piperazine compounds | LES LABORATOIRES SERVIER (FR) | 2006-10-05 | — | — | US | disclosed |
| EP-1707564-A2 | Indanyl-piperazine derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2006-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223830-A1 | Indanyl-piperazine compounds | HTR4, NR4A1, NR4A3 | KDM4E 1559/4885TP53 3984/4885CD274 2158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.