Benzamidine

Benzamidine

SCHEMBL482740

N=C(N)c1ccccc1.c1ccc(C2=NN2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.61
F10 P00742 1/20 0.61
F12 P00748 1/20 0.61
F7 P08709 1/20 0.61
F3 P13726 1/20 0.61
PKM P14618 1/20 0.61
BLM P54132 1/20 0.59
WDR5 P61964 1/20 0.59
PRSS1 P07477 4/20 0.57
PRSS2 P07478 3/20 0.57
PRSS3 P35030 3/20 0.57
C1S P09871 1/20 0.57
RECQL P46063 1/20 0.57
KMT2A Q03164 1/20 0.57
NQO2 P16083 7/20 0.49
PLAU P00749 1/20 0.43
KLK1 P06870 1/20 0.40
KLK5 Q9Y337 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL28438673 0.81 WDR5 (0.86) F2F10F12F7F3
Biphenyl SCHEMBL2456187 0.79 BLM (0.85) F2F10F12F7F3
SCHEMBL1047773 0.78
Benzamidine SCHEMBL23067876 0.78 F2 (1.00) F2F10F12F7F3
SCHEMBL18557033 0.78 F2 (1.00) F2F10F12F7F3
Benzamidine SCHEMBL9207 0.78
Benzamidine SCHEMBL27781057 0.78 F2 (1.00) F2F10F12F7F3
Benzamidine SCHEMBL6861235 0.76 BLM (1.00) F2F10F12F7F3
SCHEMBL21679634 0.76 RAB9A (0.46) KMT2A
Benzamidine SCHEMBL23235801 0.76 BLM (1.00) F2F10F12F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8247577-B2 Optical recording material and cyanine compound ADEKA CORPORATION (JP) 2012-08-21 US disclosed
EP-2020302-B1 OPTICAL RECORDING MATERIAL AND CYANINE COMPOUND ADEKA CORP (JP) 2012-02-08 EP disclosed
EP-1772282-B1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIUM ADEKA CORP (JP) 2012-02-01 EP disclosed
EP-1652892-B1 CYANINE COMPOUNDS, OPTICAL RECORDING MATERIALS AND OPTICAL RECORDING MEDIA ADEKA CORP (JP) 2010-07-14 EP disclosed
US-20100080947-A1 OPTICAL RECORDING MEDIUM ADEKA CORPORATION (JP) 2010-04-01 US disclosed
US-7674569-B2 Optical recording material and optical recording medium ADEKA CORPORATION (JP) 2010-03-09 US disclosed
US-7553604-B2 Cyanine compound, optical recording material, and optical recording medium ADEKA CORPORATION (JP) 2009-06-30 US disclosed
US-20090123686-A1 OPTICAL RECORDING MATERIAL AND CYANINE COMPOUND ADEKA CORPORATION (JP) 2009-05-14 US disclosed
EP-2020302-A1 OPTICAL RECORDING MATERIAL AND CYANINE COMPOUND Adeka Corporation (JP) 2009-02-04 EP disclosed
EP-1505125-B1 Cyanine compound, optical recording material, and optical recording medium ADEKA CORP (JP) 2009-01-07 EP disclosed
US-20080033179-A1 Optical Recording Material and Optical Recording Medium ADEKA CORPORATION (JP) 2008-02-07 US disclosed
EP-1772282-A1 OPTICAL RECORDING MATERIAL AND OPTICAL RECORDING MEDIUM Adeka Corporation (JP) 2007-04-11 EP disclosed
US-20070048486-A1 Dye material, optical recording medium using the same, and method of manufacturing the optical recording medium TDK CORPORATION (JP) 2007-03-01 US disclosed
EP-1757661-A1 Dye material, optical recording medium using the same, and method of manufacturing the optical recording medium TDK Corporation (JP) 2007-02-28 EP disclosed
US-20060286483-A1 Cyanine compounds, optical recording materials and optical recording media ASAHI DENKA CO., LTD. (JP) 2006-12-21 US disclosed
EP-1652892-A1 CYANINE COMPOUNDS, OPTICAL RECORDING MATERIALS AND OPTICAL RECORDING MEDIA Asahi Denka Co., Ltd. (JP) 2006-05-03 EP disclosed
US-20050031993-A1 Cyanine compound, optical recording material, and optical recording medium ASAHI DENKA CO., LTD. (JP) 2005-02-10 US disclosed
EP-1505125-A1 Cyanine compound, optical recording material, and optical recording medium Asahi Denka Co., Ltd. (JP) 2005-02-09 EP disclosed
US-4980260-A Heat pressing FUJI PHOTO FILM CO., LTD. (JP) 1990-12-25 US disclosed
EP-0199323-A2 4-Substituted aminoalkylidene-3-aryl-5(4H) isoxazolines, process for their preparation, medicaments containing them and their use HOECHST AKTIENGESELLSCHAFT (DE) 1986-10-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050031993-A1 Cyanine compound, optical recording material, and optical recording medium CHRM1, KCNB1, KCNB2 F2 1227/4885F10 500/4885F12 216/4885
US-20060286483-A1 Cyanine compounds, optical recording materials and optical recording media CHRM1, CRY2, KCNN1 F2 901/4885F10 402/4885F12 300/4885
US-20080033179-A1 Optical Recording Material and Optical Recording Medium OR10J3, HCN3, CHRM4 F2 1517/4885F10 189/4885F12 170/4885
US-20090123686-A1 OPTICAL RECORDING MATERIAL AND CYANINE COMPOUND CHRM1, CRY2, CHRM2 F2 801/4885F10 350/4885F12 89/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.