Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18198955 | 1.00 | RAB9A (0.39) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL29299404 | 1.00 | RAB9A (0.39) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL18198958 | 0.98 | RAB9A (0.38) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL6902225 | 0.95 | ALDH1A1 (0.41) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL1076577 | 0.95 | ALDH1A1 (0.41) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL6387239 | 0.95 | ALDH1A1 (0.41) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL10735746 | 0.78 | MAPT (0.47) | RAB9ANPC1MAPTSMN1; SMN2EGFR | |
| SCHEMBL8650664 | 0.76 | NPC1 (0.36) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL8650660 | 0.76 | NPC1 (0.36) | RAB9ANPC1MAPTSMN1; SMN2HPGD | |
| SCHEMBL9512837 | 0.76 | NPC1 (0.33) | RAB9ANPC1MAPTSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081310-A | PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-01-14 | — | — | US | claimed |
| EP-0090976-B1 | 2,2-DIHALO-6-HALO-6(1-HALOISOBUTYL)CYCLOHEXANONE | MITSUBISHI KASEI CORPORATION (JP) | 1985-12-11 | — | — | EP | claimed |
| US-4499306-A | HALOGENATION OF 2-ISOBUTYLIDENE CYCLOHEXANONE IN PRESENCE OF CATALST | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1985-02-12 | — | — | US | claimed |
| EP-0090976-A2 | 2,2-Dihalo-6-halo-6(1-haloisobutyl)cyclohexanone | MITSUBISHI KASEI CORPORATION (JP) | 1983-10-12 | — | — | EP | claimed |
| JP-59082377-A | — | — | None | — | — | JP | disclosed |
| JP-58174339-A | — | — | None | — | — | JP | disclosed |
| JP-59076078-A | — | — | None | — | — | JP | disclosed |
| US-20240229089-A1 | A process for enzymatic synthesis of amides from amines and carboxylic acids or esters | XP CHEMISTRIES AB (SE) | 2024-07-11 | — | — | US | disclosed |
| EP-4308714-A1 | A PROCESS FOR ENZYMATIC SYNTHESIS OF AMIDES FROM AMINES AND CARBOXYLIC ACIDS OR ESTERS | XP Chemistries AB (SE) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022229314-A1 | A PROCESS FOR ENZYMATIC SYNTHESIS OF AMIDES FROM AMINES AND CARBOXYLIC ACIDS OR ESTERS | XP CHEMISTRIES AB (SE) | 2022-11-03 | — | — | WO | disclosed |
| US-20170246155-A1 | COMPOSITIONS AND METHODS FOR SELECTIVELY DEPLETING SENESCENT CELLS | BIOVENTURES, LLC | 2017-08-31 | — | — | US | disclosed |
| US-7344740-B2 | Methods and apparatus to prevent, treat, and cure the symptoms of nausea caused by chemotherapy treatments of human cancers | INHALATION, INC. (US) | 2008-03-18 | — | — | US | disclosed |
| US-4647677-A | Process for preparing 2,3-dihydro-7-aminobenzofurans | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1987-03-03 | — | — | US | disclosed |
| US-4594438-A | Dehydrohalogenation heating of 2,2,6-tri-halo-6-(1-halisobutyl)cyclohexanone | MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| EP-0090976-B1 | 2,2-DIHALO-6-HALO-6(1-HALOISOBUTYL)CYCLOHEXANONE | MITSUBISHI KASEI CORPORATION (JP) | 1985-12-11 | — | — | EP | disclosed |
| US-4499306-A | HALOGENATION OF 2-ISOBUTYLIDENE CYCLOHEXANONE IN PRESENCE OF CATALST | MITSUBISHI CHEMICAL INDUSTRIES LTD. (JP) | 1985-02-12 | — | — | US | disclosed |
| JP-S5982377-A | PREPARATION OF 2,2-DIMETHYL-2,3-DIHYDRO-7- HYDROXYBENZOFURAN | MITSUBISHI CHEM IND LTD | 1984-05-12 | — | — | JP | disclosed |
| JP-S5976078-A | PREPARATION OF 2,2-DIMETHYL-2,3-DIHYDRO-7-HALOBENZOFURAN | MITSUBISHI CHEM IND LTD | 1984-04-28 | — | — | JP | disclosed |
| JP-S58174339-A | 2,2-DIHALO-6-HALO-6-(1-HALOISOBUTYL)CYCLOHEXANONE | MITSUBISHI CHEM IND LTD | 1983-10-13 | — | — | JP | disclosed |
| EP-0090976-A2 | 2,2-Dihalo-6-halo-6(1-haloisobutyl)cyclohexanone | MITSUBISHI KASEI CORPORATION (JP) | 1983-10-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170246155-A1 | COMPOSITIONS AND METHODS FOR SELECTIVELY DEPLETING SENESCENT CELLS | CD47, MCL1, LIMS1 | RAB9A 1036/4885NPC1 1272/4885MAPT 3398/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.