Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809609 | 0.96 | ALDH1A1 (0.34) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL812178 | 0.96 | ALDH1A1 (0.34) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL6901403 | 0.86 | TP53 (0.34) | ALDH1A1KMT2AHTT | |
| SCHEMBL6901400 | 0.86 | TP53 (0.34) | ALDH1A1KMT2AHTT | |
| SCHEMBL6902528 | 0.83 | ADH1B (0.35) | ALDH1A1HTT | |
| SCHEMBL6902527 | 0.83 | ADH1B (0.35) | ALDH1A1HTT | |
| SCHEMBL6900658 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL1077341 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL1078383 | 0.79 | ALDH1A1 (0.35) | NPC1RAB9AHPGDMAPTSMN1; SMN2 | |
| SCHEMBL11040965 | 0.76 | RAB9A (0.36) | NPC1RAB9AHPGDMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081310-A | PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-01-14 | — | — | US | claimed |
| EP-0409530-B1 | Catalytic preparation of optically active ketones | TAKASAGO PERFUMERY CO LTD (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5081310-A | PROCESS FOR PREPARING OPTICALLY ACTIVE KETONES | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0409530-A1 | Catalytic preparation of optically active ketones | Takasago International Corporation (JP) | 1991-01-23 | — | — | EP | disclosed |