Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902225 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL1076577 | 1.00 | ALDH1A1 (0.41) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL4827581 | 0.95 | RAB9A (0.39) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL18198955 | 0.95 | RAB9A (0.39) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL18198958 | 0.93 | RAB9A (0.38) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL10735746 | 0.83 | MAPT (0.47) | ALDH1A1HTTMAPTSMN1; SMN2NPC1 | |
| SCHEMBL6900658 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL1077341 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL809609 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HTTAKR1C3AKR1C1MAPT | |
| SCHEMBL812178 | 0.76 | ALDH1A1 (0.34) | ALDH1A1HTTAKR1C3AKR1C1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1737005-A | Chiral diphosphor compound an transition metal complex thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-22 | — | — | CN | disclosed |
| US-20050288523-A1 | Chiral diphosphorus compounds and transition metal complexes thereof | LANXESS DEUTSCHLAND GMBH (DE) | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288523-A1 | Chiral diphosphorus compounds and transition metal complexes thereof | PIN1, CDIPT, DDT | ALDH1A1 2617/4885HTT 3938/4885AKR1C3 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.