Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 6/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868461 | 0.86 | PIM1 (0.38) | PIM1APPIAPPTSHRCYP2D6 | |
| SCHEMBL9618306 | 0.85 | TSHR (0.57) | TSHRCYP2D6HIF1ACA2HSD17B10 | |
| SCHEMBL21556903 | 0.82 | IAPP (0.45) | IAPPCA2HSD17B10ADAMTS4ALDH1A1 | |
| SCHEMBL14868467 | 0.80 | TPH1 (0.35) | PIM1APPIAPPTSHRCYP2D6 | |
| SCHEMBL14868501 | 0.79 | IAPP (0.36) | PIM1APPIAPPTSHRCYP2D6 | |
| SCHEMBL12765730 | 0.76 | TSHR (0.67) | APPIAPPTSHRCYP2D6HIF1A | |
| SCHEMBL14868512 | 0.75 | IAPP (0.38) | PIM1APPIAPPTSHRCYP2D6 | |
| SCHEMBL9312564 | 0.75 | LMNA (0.44) | IAPPCA2HSD17B10ADAMTS4ALDH1A1 | |
| SCHEMBL21408116 | 0.74 | HPGD (0.37) | CYP2D6CA2ALDH1A1HPGDMTNR1A | |
| SCHEMBL18255173 | 0.74 | IAPP (0.56) | PIM1IAPPMTNR1AALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381542-B2 | Nucleic acids encoding a biogenic amine receptor | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2008-06-03 | — | — | US | disclosed |
| US-20040072187-A1 | Novel mammalian receptor genes and uses | OREGON HEALTH & SCIENCE UNIVERSITY | 2004-04-15 | — | — | US | disclosed |