Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 7/20 | 0.53 |
| ▸ | CA2 | P00918 | 7/20 | 0.53 |
| ▸ | CA9 | Q16790 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | MPO | P05164 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827827 | 0.85 | PIM1 (0.41) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL502196 | 0.81 | TSHR (0.53) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL3926227 | 0.81 | MPO (0.55) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL10425013 | 0.80 | MTNR1A (0.38) | TSHRCYP2D6HIF1AKDM4EPKM | |
| SCHEMBL8488364 | 0.80 | HPGD (0.46) | CYP2D6KDM4EPKMCYP2C19ALDH1A1 | |
| SCHEMBL10425014 | 0.80 | PNMT (0.39) | TSHRCYP2D6HIF1AKDM4ETAAR1 | |
| Hydrochloric Acid SCHEMBL6997774 | 0.79 | MPO (0.53) | TSHRCYP2D6HIF1ACA12CA2 | |
| SCHEMBL4014038 | 0.78 | ALDH1A1 (0.54) | CA2KDM4EPKMTAAR1MAPT | |
| SCHEMBL31344502 | 0.78 | RIPK1 (0.49) | TSHRMPOPKMTAAR1MAPT | |
| SCHEMBL10310299 | 0.78 | RIPK1 (0.49) | TSHRMPOPKMTAAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4297449-A | — | — | None | — | — | JP | disclosed |
| US-20210371403-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS INC. | 2021-12-02 | — | — | US | disclosed |
| US-20210299070-A1 | METHODS OF TREATING CREATINE TRANSPORTER DEFICIENCY | JNANA THERAPEUTICS INC. | 2021-09-30 | — | — | US | disclosed |
| WO-2020061473-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | JNANA THERAPEUTICS, INC. (US) | 2020-03-26 | — | — | WO | disclosed |
| JP-H04297449-A | N-HYDROXYBENZYLGUANIDINE DERIVATIVE AND GERMICIDE FOR AGRICULTURE AND HORTICULTURE | HOKKO CHEM IND CO LTD | 1992-10-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210299070-A1 | METHODS OF TREATING CREATINE TRANSPORTER DEFICIENCY | SLC19A1, SLC1A5, SLC1A2 | TSHR 2720/4885CYP2D6 2985/4885HIF1A 3335/4885 |
| US-20210371403-A1 | SMALL MOLECULES TARGETING MUTANT MAMMALIAN PROTEINS | SNRPE, G3BP1, G3BP2 | TSHR 4032/4885CYP2D6 4671/4885HIF1A 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.