Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4828263 | 0.94 | KDM4E (0.54) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL4824629 | 0.90 | SMN1; SMN2 (0.54) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL4823915 | 0.86 | TOP2A (0.51) | ALDH1A1MAPTKDM4EPOLBLMNA | |
| SCHEMBL21186140 | 0.85 | SMN1; SMN2 (0.50) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL11136638 | 0.83 | LTA4H (0.46) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL11317810 | 0.83 | MAPT (0.61) | ALDH1A1MAPTHSD17B10GAASMN1; SMN2 | |
| SCHEMBL9756822 | 0.83 | LMNA (0.60) | ALDH1A1MAPTKDM4ETSHRSMN1; SMN2 | |
| SCHEMBL8739445 | 0.81 | SMN1; SMN2 (0.47) | ALDH1A1MAPTHSD17B10KDM4EGAA | |
| SCHEMBL4828296 | 0.81 | ALDH1A1 (0.51) | ALDH1A1MAPTPOLBLMNACA1 | |
| SCHEMBL4826837 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTHSD17B10KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | claimed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | claimed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-7384432-B2 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2008-06-10 | — | — | US | disclosed |
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | L'OREAL S.A. (FR) | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060021159-A1 | Secondary para-phenylenediamines having a carboxyl group, dye compositions comprising the same, and dyeing processes using the compositions | KRT18, CDC73, JUP | ALDH1A1 509/4885MAPT 1947/4885HSD17B10 1289/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.