SCHEMBL4828448

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4828445	1.00	ALDH1A1 (0.49)	ALDH1A1HTTNAPRTMEN1KMT2A
	Benzene SCHEMBL27436197	0.77	ALDH1A1 (0.56)	ALDH1A1HTTNAPRTMEN1KMT2A
	SCHEMBL105986	0.77	ALDH1A1 (0.56)	ALDH1A1HTTNAPRTMEN1KMT2A
	SCHEMBL1370683	0.77	ALDH1A1 (0.56)	ALDH1A1HTTNAPRTMEN1KMT2A
	SCHEMBL2680021	0.77	ALDH1A1 (0.56)	ALDH1A1HTTNAPRTMEN1KMT2A
	SCHEMBL6997673	0.77	HTT (0.67)	ALDH1A1HTTNAPRTMEN1KMT2A
	SCHEMBL6997670	0.77	HTT (0.67)	ALDH1A1HTTNAPRTMEN1KMT2A
	Water SCHEMBL27459091	0.76	ALDH1A1 (0.54)	ALDH1A1HTTNAPRTMEN1KMT2A
	SCHEMBL4452292	0.76	ALDH5A1 (0.56)	ALDH1A1HTTMEN1KMT2ACYP3A4
	Ammonia Solution, Strong SCHEMBL27875840	0.76	ALDH1A1 (0.54)	ALDH1A1HTTNAPRTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.