Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 7/20 | 0.34 |
| ▸ | RBP4 | P02753 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2956860 | 0.88 | SPR (0.36) | SPRRBP4 | |
| SCHEMBL16242496 | 0.86 | SPR (0.32) | SPRHPGD | |
| SCHEMBL4837047 | 0.82 | NPC1 (0.36) | — | |
| SCHEMBL16242493 | 0.79 | FAAH (0.42) | — | |
| SCHEMBL4829941 | 0.76 | GRM4 (0.34) | HPGD | |
| SCHEMBL2955527 | 0.76 | GAA (0.43) | RBP4HPGD | |
| SCHEMBL2966049 | 0.74 | GAA (0.38) | SPRHPGD | |
| SCHEMBL16242373 | 0.73 | HPGD (0.34) | HPGD | |
| SCHEMBL1573644 | 0.73 | RAB9A (0.39) | RBP4HPGD | |
| SCHEMBL2965248 | 0.71 | NPC1 (0.36) | HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937648-B1 | DIACYL INDAZOL DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI SA (FR) | 2014-11-26 | — | — | EP | disclosed |
| EP-1937648-A1 | DIACYL INDAZOL DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | sanofi-aventis (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007042178-A1 | DIACYL INDAZOL DERIVATIVES AS LIPASE AND PHOSPHOLIPASE INHIBITORS | SANOFI-AVENTIS (DE) | 2007-04-19 | — | — | WO | disclosed |