Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 9/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.56 |
| ▸ | DPP4 | P27487 | 2/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.42 |
| ▸ | MAP4K1 | Q92918 | 2/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4827538 | 1.00 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| SCHEMBL4827864 | 0.86 | CHRNA3 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| SCHEMBL4828940 | 0.86 | CHRNA3 (0.46) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| SCHEMBL649095 | 0.82 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| Hydrochloric Acid SCHEMBL645632 | 0.81 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| SCHEMBL4824732 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL4823979 | 0.81 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL31421618 | 0.80 | CHRNB2 (0.54) | CHRNB2CHRNA4CHRNB4CHRNA3DPP4 | |
| SCHEMBL6501263 | 0.79 | NOTUM (0.56) | DPP4PRKCQMAP4K1LRRK2 | |
| SCHEMBL6496702 | 0.79 | NOTUM (0.56) | DPP4PRKCQMAP4K1LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7332504-B2 | Heterocyclic substituted aminoazacycles useful as central nervous system agents | ABBOTT LABORATORIES (US) | 2008-02-19 | — | — | US | claimed |
| US-7332504-B2 | Heterocyclic substituted aminoazacycles useful as central nervous system agents | ABBOTT LABORATORIES (US) | 2008-02-19 | — | — | US | disclosed |