SCHEMBL48292

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL48299	0.94	HMGCR (0.50)	HMGCRHTTHPGDSTTRHTR2A
	SCHEMBL48212	0.83	HTT (0.64)	HMGCRHTTTTRHTR2ACYP3A4
	SCHEMBL48227	0.77	HTT (0.64)	HMGCRHTTTTRHTR2ACYP3A4
	SCHEMBL14525270	0.73	HPGDS (0.47)	HMGCRHPGDSHTR2AHSP90AA1CYP3A4
	SCHEMBL21798808	0.73	TAAR1 (0.52)	HMGCRHTR2ACYP3A4TAAR1
	SCHEMBL17166187	0.73	HPGDS (0.48)	HMGCRHPGDSHTR2ACYP3A4GSK3B
	SCHEMBL8544834	0.69	CYP3A4 (0.55)	HMGCRHTTHPGDSCYP3A4KDM4E
	SCHEMBL31336022	0.68	HMGCR (0.54)	HMGCRHTTHSP90AA1PKMCYP3A4
	SCHEMBL9417829	0.68	HMGCR (0.54)	HMGCRHTTHSP90AA1CYP3A4KDM4E
	SCHEMBL47985	0.68	HTT (0.58)	HMGCRHTTTTRHTR2ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.