Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 10/20 | 0.58 |
| ▸ | CA1 | P00915 | 10/20 | 0.58 |
| ▸ | CA2 | P00918 | 10/20 | 0.58 |
| ▸ | CA9 | Q16790 | 10/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9412855 | 0.86 | CA12 (0.75) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13073503 | 0.84 | CA12 (0.76) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL1810465 | 0.82 | TDP1 (0.74) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL8819529 | 0.80 | TDP1 (0.71) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL14253654 | 0.79 | CA12 (0.74) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL13110899 | 0.79 | TDP1 (0.67) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL9412852 | 0.79 | TDP1 (0.74) | CA12CA1CA2CA9TDP1 | |
| Biotin SCHEMBL446893 | 0.78 | TDP1 (0.79) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL6372736 | 0.78 | CA12 (0.79) | CA12CA1CA2CA9TDP1 | |
| SCHEMBL5808600 | 0.78 | TDP1 (0.57) | CA12CA1CA2CA9TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7449558-B2 | Site-specific labelling of proteins | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2008-11-11 | — | — | US | claimed |
| US-20050158804-A1 | Site-specific labelling of proteins | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2005-07-21 | — | — | US | claimed |
| US-7449558-B2 | Site-specific labelling of proteins | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2008-11-11 | — | — | US | disclosed |
| US-20050158804-A1 | Site-specific labelling of proteins | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2005-07-21 | — | — | US | disclosed |