Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | NQO1 | P15559 | 1/20 | 0.31 |
| ▸ | IAPP | P10997 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.30 |
| ▸ | NSD2 | O96028 | 1/20 | 0.30 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1258869 | 0.78 | SMN1; SMN2 (0.36) | SMN1; SMN2CYP1A2CYP3A4CYP2C19SLC22A12 | |
| SCHEMBL1258872 | 0.78 | CYP1A2 (0.50) | SMN1; SMN2KDM4EHSD17B10GAACYP1A2 | |
| SCHEMBL24440124 | 0.76 | GAA (0.43) | TDP1SMN1; SMN2KDM4EHSD17B10GAA | |
| SCHEMBL10999349 | 0.72 | TSHR (0.41) | TDP1SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL27035746 | 0.72 | ALDH1A1 (0.37) | SMN1; SMN2KDM4ECYP1A2CYP3A4CYP2C19 | |
| Ethylene SCHEMBL7414602 | 0.72 | CD44 (0.39) | TDP1SMN1; SMN2KDM4EHSD17B10GAA | |
| Propionic Acid SCHEMBL29018259 | 0.70 | FFAR3 (0.53) | SMN1; SMN2HSD17B10GAACYP1A2CYP3A4 | |
| SCHEMBL14250470 | 0.69 | LMNA (0.44) | SMN1; SMN2KDM4EGAAIAPPALDH1A1 | |
| SCHEMBL3456090 | 0.69 | NOS2 (0.43) | KDM4ECYP1A2TDP2NSD2HSP90AA1 | |
| SCHEMBL12214127 | 0.69 | KDM4E (0.42) | SMN1; SMN2KDM4EHSD17B10GAACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7404975-B2 | Moringa crude extracts and their derived fractions with antifungal activities | ACADEMIA SINICA (TW) | 2008-07-29 | — | — | US | disclosed |
| US-20070264366-A1 | Moringa crude extracts and their derived fractions with antifungal activities | ACADEMIA SINICA (TW) | 2007-11-15 | — | — | US | disclosed |