Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CD44 | P16070 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATP4A | P20648 | 1/20 | 0.35 |
| ▸ | ATP4B | P51164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28474465 | 0.78 | KDM4E (0.51) | CD44ALDH1A1CYP3A4TDP1KDM4E | |
| Ethylene SCHEMBL27537107 | 0.77 | CD44 (0.48) | CD44ALDH1A1HSD17B10CYP3A4TDP1 | |
| Ethylene SCHEMBL7412898 | 0.76 | TDP1 (0.49) | ALDH1A1HSD17B10TDP1L3MBTL1KDM4E | |
| Ethylene SCHEMBL7409706 | 0.76 | ALDH1A1 (0.34) | ALDH1A1CYP3A4L3MBTL1KDM4E | |
| SCHEMBL12214127 | 0.75 | KDM4E (0.42) | ALDH1A1HSD17B10KDM4EHPGDSLC22A12 | |
| SCHEMBL6344760 | 0.73 | CD44 (0.52) | CD44ALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL30417664 | 0.73 | CD44 (0.52) | CD44ALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL2009339 | 0.73 | CD44 (0.52) | CD44ALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL31606366 | 0.73 | CD44 (0.52) | CD44ALDH1A1HSD17B10CYP3A4TDP1 | |
| SCHEMBL4830174 | 0.72 | TDP1 (0.36) | ALDH1A1HSD17B10CYP3A4TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640080-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS. | SYNTEX INC (US) | 1995-03-01 | — | — | EP | disclosed |
| US-5380739-A | Angiotensin II antagonists | SYNTEX (U.S.A.) INC. (US) | 1995-01-10 | — | — | US | disclosed |
| WO-1993023391-A1 | SUBSTITUTED INDOLES AND AZAINDOLES AS ANGIOTENSIN II ANTAGONISTS | SYNTEX (U.S.A.) INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| US-5212195-A | Substituted indole antagonists derivatives which are angiotensin II | SYNTEX (U.S.A.) INC. (US) | 1993-05-18 | — | — | US | disclosed |