SCHEMBL48306

SCHEMBL48306

ClCCCOC1CCCCO1

nearest known ligand 0.51

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
KDM4C Q9H3R0 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.40
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
P2RX3 P56373 4/20 0.32
TGFBR1 P36897 1/20 0.31
KCNH2 Q12809 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL811117 0.96 MEN1 (0.51) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL738953 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL4312808 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL16005690 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL19173031 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1801722 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL1632799 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL8928066 0.94 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL11024894 0.90 MEN1 (0.54) MEN1KMT2AKDM4CL3MBTL1NPC1
SCHEMBL319842 0.88 MEN1 (0.43) MEN1KMT2AKDM4CL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117447378-B Cilobodoxin chirality Process for the preparation of intermediates 斯坦德药典标准物质研发(湖北)有限公司 2025-02-11 CN claimed
CN-109336740-B Preparation method of 4,4, 4-trifluoro-1-butanol 湖南有色郴州氟化学有限公司 2021-08-17 CN claimed
CN-117157271-B Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium 株式会社力森诺科 2026-05-15 CN disclosed
US-20260070882-A1 PHOTOSTABLE MIMICS OF MACULAR PIGMENT JOHNSON & JOHNSON VISION CARE (US) 2026-03-12 US disclosed
US-20260062386-A1 POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT JOHNSON & JOHNSON VISION CARE (US) 2026-03-05 US disclosed
US-12509428-B2 Polymerizable fused tricyclic compounds as absorbers of UV and visible light JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-12-30 US disclosed
US-12497379-B2 Photostable mimics of macular pigment JOHNSON & JOHNSON VISION CARE, INC. (US) 2025-12-16 US disclosed
WO-2025079989-A1 PYRAZOLO[3,4-B]PYRIDINE DERIVATIVE OR SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME 주식회사유한양행 2025-04-17 WO disclosed
CN-117447378-B Cilobodoxin chirality Process for the preparation of intermediates 斯坦德药典标准物质研发(湖北)有限公司 2025-02-11 CN disclosed
CN-115038685-B Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium 株式会社力森诺科 2024-12-13 CN disclosed
CN-119137093-A Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium 株式会社力森诺科 2024-12-13 CN disclosed
US-4696929-A Derivative of piperazine having anti-allergic and anti-inflammatory action TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1987-09-29 US disclosed
WO-1987001706-A2 C20 THROUGH C26 AMINO STEROIDS THE UPJOHN COMPANY (US) 1987-03-26 WO disclosed
EP-0188803-A1 Piperazine derivative TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1986-07-30 EP disclosed
US-4413006-A N-Aryl-N-phenoxy-alkyl-piperazine compounds useful in decreasing intracranial pressure TANABE SEIYAKU CO., LTD. (JP) 1983-11-01 US disclosed
EP-0034284-B1 PIPERAZINE DERIVATIVE, PROCESSES FOR PREPARING THE SAME AND THERAPEUTIC COMPOSITIONS CONTAINING IT Tanabe Seiyaku Co., Ltd. (JP) 1983-10-05 EP disclosed
EP-0034284-A2 Piperazine derivative, processes for preparing the same and therapeutic compositions containing it Tanabe Seiyaku Co., Ltd. (JP) 1981-08-26 EP disclosed
US-4218375-A SEDATIVES, ANTIHISTAMINES ROUSSEL UCLAF (FR) 1980-08-19 US disclosed
US-4154731-A ANTISECRETORY AGENTS, ANTIINFLAMMATORY AGENTS, ANALGESICS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1979-05-15 US disclosed
US-4105670-A ANTISECRETORY, ANTIINFLAMMATORY, ANALGESIC, DECARBOXYLATION TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1978-08-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260062386-A1 POLYMERIZABLE FUSED TRICYCLIC COMPOUNDS AS ABSORBERS OF UV AND VISIBLE LIGHT ERCC1, MCM6, GPR6 MEN1 3166/4885KMT2A 4362/4885KDM4C 2884/4885
US-20260070882-A1 PHOTOSTABLE MIMICS OF MACULAR PIGMENT CRY1, CRY2, XPA MEN1 458/4885KMT2A 3404/4885KDM4C 3491/4885
US-12497379-B2 Photostable mimics of macular pigment CRY1, PDE6C, PDE6A MEN1 50/4885KMT2A 2296/4885KDM4C 3223/4885
US-12509428-B2 Polymerizable fused tricyclic compounds as absorbers of UV and visible light ERCC1, OGG1, ERCC4 MEN1 3553/4885KMT2A 3086/4885KDM4C 290/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.