Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4967601 | 0.87 | AQP1 (0.47) | AQP1 | |
| SCHEMBL4836377 | 0.87 | AQP1 (0.36) | AQP1MAPTMAPK1NPSR1TDP1 | |
| SCHEMBL4713102 | 0.79 | AQP1 (0.54) | AQP1MAPTMAPK1NPSR1TDP1 | |
| SCHEMBL4970746 | 0.78 | AQP1 (0.46) | AQP1MAPK1 | |
| SCHEMBL4713099 | 0.77 | AQP1 (0.54) | AQP1L3MBTL1 | |
| SCHEMBL4791163 | 0.76 | AQP1 (0.36) | AQP1 | |
| SCHEMBL4225696 | 0.76 | AQP1 (0.82) | AQP1 | |
| SCHEMBL4232178 | 0.76 | AQP1 (0.83) | AQP1MAPTMAPK1NPSR1TDP1 | |
| SCHEMBL4232185 | 0.74 | AQP1 (0.67) | AQP1 | |
| SCHEMBL4968821 | 0.74 | AQP1 (0.38) | AQP1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1871356-A1 | DIHYDROBENZOFURAN DERIVATIVES AND USES THEREOF | Wyeth a Corporation of the State of Delaware (US) | 2008-01-02 | — | — | EP | disclosed |
| WO-2006116170-A1 | DIHYDROBENZOFURAN DERIVATIVES AND USES THEREOF | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |