Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 4/20 | 0.32 |
| ▸ | HTR7 | P34969 | 4/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4830774 | 0.87 | AQP1 (0.50) | AQP1 | |
| SCHEMBL4791163 | 0.84 | AQP1 (0.36) | AQP1HTR7 | |
| SCHEMBL4974465 | 0.84 | MAPK14 (0.37) | — | |
| SCHEMBL4968821 | 0.81 | AQP1 (0.38) | AQP1CNR1 | |
| SCHEMBL4765146 | 0.79 | AQP1 (0.50) | AQP1HTR1AHTR7CNR1 | |
| SCHEMBL4765139 | 0.76 | AQP1 (0.49) | AQP1HTR1AHTR7CNR1 | |
| SCHEMBL4228615 | 0.76 | AQP1 (0.58) | AQP1CNR1 | |
| SCHEMBL4222332 | 0.76 | AQP1 (0.76) | AQP1CNR1 | |
| SCHEMBL4228623 | 0.76 | AQP1 (0.58) | AQP1CNR1 | |
| SCHEMBL4224838 | 0.75 | AQP1 (0.79) | AQP1HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879569-A2 | THERAPEUTIC COMBINATIONS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS | Wyeth (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006116221-A2 | THERAPEUTIC COMBINATIONS FOR THE TREATMENT OR PREVENTION OF PSYCHOTIC DISORDERS | WYETH (US) | 2006-11-02 | — | — | WO | disclosed |