Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.56 |
| ▸ | RORC | P51449 | 1/20 | 0.56 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.51 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | BMP1 | P13497 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5461692 | 0.84 | RORC (0.52) | ESR1RORCCYP2C8CYP2C18TSHR | |
| SCHEMBL2603075 | 0.81 | ESR1 (0.71) | ESR1RORCNR3C1CYP2C8CYP2C18 | |
| SCHEMBL11737973 | 0.80 | ESR1 (0.67) | ESR1NR3C1CYP2C8CYP2C18TSHR | |
| SCHEMBL27789021 | 0.78 | KMT2A (0.55) | ESR1NR3C1CYP2C8CYP2C18BACE1 | |
| SCHEMBL3156533 | 0.77 | NR3C1 (0.51) | ESR1RORCNR3C1 | |
| SCHEMBL23859846 | 0.76 | RORC (0.46) | ESR1RORCKMT2A | |
| SCHEMBL6257441 | 0.76 | SMN1; SMN2 (0.68) | CYP2C8CYP2C18BACE1TSHRCYP2C9 | |
| SCHEMBL2006245 | 0.76 | ESR1 (0.60) | ESR1TSHRMAPK1KMT2AHSD17B10 | |
| SCHEMBL2018485 | 0.75 | RORC (0.38) | RORCNR3C1CYP2C8CYP2C18BACE1 | |
| SCHEMBL5469170 | 0.74 | PKM (0.57) | RORCCYP2C18KMT2ACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186753-B1 | Pharmaceutical compounds | NICOX S.A. (FR) | 2007-03-06 | — | — | US | claimed |
| EP-1309354-A2 | THERAPEUTIC POLYESTERS AND POLYAMIDES | Rutgers, The State University (US) | 2003-05-14 | — | — | EP | claimed |
| JP-2003515526-A | — | — | 2003-05-07 | — | — | JP | claimed |
| JP-2002541233-A | — | — | 2002-12-03 | — | — | JP | claimed |
| EP-1252133-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-10-30 | — | — | EP | claimed |
| EP-1192129-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-04-03 | — | — | EP | claimed |
| WO-2002009768-A2 | THERAPEUTIC POLYESTERS AND POLYAMIDES | RUTGERS, THE STATE UNIVERSITY (US) | 2002-02-07 | — | — | WO | claimed |
| EP-1169294-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-01-09 | — | — | EP | claimed |
| EP-1169298-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2002-01-09 | — | — | EP | claimed |
| WO-2001012584-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2001-02-22 | — | — | WO | claimed |
| WO-2000061549-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061541-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| WO-2000061537-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | claimed |
| EP-4157357-A1 | ANTIBODY-DRUG CONJUGATES | Spirea Limited (GB) | 2023-04-05 | — | — | EP | disclosed |
| WO-2021240155-A1 | ANTIBODY-DRUG CONJUGATES | SPIREA LIMITED (GB) | 2021-12-02 | — | — | WO | disclosed |
| EP-3565848-A1 | NITRIC OXIDE-RELEASING ALGINATES AS BIODEGRADABLE ANTIBACTERIAL SCAFFOLDS AND METHODS PERTAINING THERETO | The University of North Carolina at Chapel Hill (US) | 2019-11-13 | — | — | EP | disclosed |
| WO-2000061549-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | disclosed |
| WO-2000061541-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | disclosed |
| WO-2000061537-A2 | PHARMACEUTICAL COMPOUNDS | NICOX S.A. (FR) | 2000-10-19 | — | — | WO | disclosed |
| US-4330468-A | Water soluble monoazo dyes for nylon | IMPERIAL CHEMICAL INDUSTRIES, LIMITED (GB) | 1982-05-18 | — | — | US | disclosed |