Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GNRHR | P30968 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842258 | 0.90 | CA12 (0.40) | TRPA1GNRHRTAS2R14MAPTKMT2A | |
| SCHEMBL4844332 | 0.88 | MEN1 (0.40) | TRPA1GNRHRMAPTKMT2A | |
| SCHEMBL4843919 | 0.86 | TRPA1 (0.41) | TRPA1PKMGNRHR | |
| SCHEMBL4833989 | 0.86 | TRPA1 (0.42) | TRPA1PKMMAPT | |
| SCHEMBL4843213 | 0.84 | MAPT (0.42) | GNRHRTAS2R14MAPTSMN1; SMN2TSHR | |
| SCHEMBL4833652 | 0.83 | MAPT (0.43) | PKMGNRHRMAPTTSHR | |
| Hydrochloric Acid SCHEMBL4845617 | 0.83 | MAPT (0.41) | GNRHRMAPTSMN1; SMN2TSHR | |
| SCHEMBL4841593 | 0.82 | TRPA1 (0.40) | TRPA1 | |
| SCHEMBL4840531 | 0.81 | RORC (0.39) | TRPA1GNRHRMAPTKMT2A | |
| SCHEMBL4845609 | 0.81 | MAPT (0.41) | GNRHRMAPTSMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7465811-B2 | Indoline compounds | LABORATOIRES FOURNIER S.A. (FR) | 2008-12-16 | — | — | US | disclosed |
| US-20080119465-A1 | Novel Indoline Compounds | LABORATORIES FOURNIER S.A. (FR) | 2008-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080119465-A1 | Novel Indoline Compounds | GPR119, INSR, IRS1 | TRPA1 368/4885PKM 1415/4885GNRHR 2528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.