Sugi Predict

Sugi Predict / Compounds / SCHEMBL4833903

SCHEMBL4833903

SCHEMBL4833903

CC(=O)c1nc2ccccc2nc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 5/20 0.54
▸ ALDH1A1 P00352 5/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.51
▸ TP53 P04637 1/20 0.51
▸ KDM4E B2RXH2 4/20 0.48
▸ CYP1A2 P05177 3/20 0.48
▸ MAPK1 P28482 2/20 0.46
▸ CASP1 P29466 1/20 0.46
▸ CASP7 P55210 1/20 0.46
▸ PDE10A Q9Y233 1/20 0.46
▸ NR1H2 P55055 1/20 0.43
▸ NR1H3 Q13133 1/20 0.43
▸ HTT P42858 2/20 0.42
▸ LMNA P02545 1/20 0.42
▸ HPGD P15428 2/20 0.42
▸ GAA P10253 1/20 0.42
▸ STAT3 P40763 1/20 0.42
▸ NUDT1 P36639 1/20 0.42
▸ GPR3 P46089 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14099196 0.87 MAPT (0.62) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL29670121 0.83 ALDH1A1 (0.72) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL2056931 0.83 ALDH1A1 (0.72) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL4396535 0.82 MAPT (0.52) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL6387026 0.82 MAPT (0.52) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL47270 0.79 MAPT (0.54) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL27937220 0.79 MAPT (0.48) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL9822756 0.79 KDM4E (0.43) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL3701892 0.79 TDP1 (0.56) MAPTALDH1A1SMN1; SMN2HSD17B10TP53
SCHEMBL6386134 0.79 SMN1; SMN2 (0.56) MAPTALDH1A1SMN1; SMN2HSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103360328-B A kind of desoxyquinocetone haptens and preparation method thereof and its application CHINA AGRICULTURAL UNIVERSITY (CN) 2015-12-02 — — CN claimed
CN-103524435-B A kind of mequindox remains the haptens and complete antigen and preparation method thereof that marker takes off dioxy mequindox SOUTH CHINA AGRICULTURAL UNIVERSITY (CN) 2015-11-04 — — CN claimed
CN-102070539-B 1-oxo-2-methyl-3-(1-ethoxyl)-quinoxaline and preparation method and application thereof GENIFARM GUANGZHOU TECHNOLOGY INC 2014-02-19 — — CN claimed
CN-103524435-A Hapten and complete antigen of mequindox residual marker (dedioxo mequindox) and preparation method thereof UNIV SOUTH CHINA AGRICULT 2014-01-22 — — CN claimed
CN-102070540-B 1-oxygen-2-(1-ethoxy)-3-methyl-quinoxaline, and preparation method and application thereof GENIFARM GUANGZHOU TECHNOLOGY INC 2013-11-20 — — CN claimed
CN-103360328-A Desoxyquinocetone hapten, and preparation method and application thereof UNIV CHINA AGRICULTURAL 2013-10-23 — — CN claimed
CN-101928252-B Preparation method of 3-methyl-2-ethanol based quinoxaline UNIV CHINA AGRICULTURAL 2012-11-07 — — CN claimed
CN-102070540-A 1-oxygen-2-(1-ethoxy)-3-methyl-quinoxaline, and preparation method and application thereof GENIFARM GUANGZHOU TECHNOLOGY INC 2011-05-25 — — CN claimed
CN-102070539-A 1-oxo-2-methyl-3-(1-ethoxyl)-quinoxaline and preparation method and application thereof GENIFARM GUANGZHOU TECHNOLOGY INC 2011-05-25 — — CN claimed
CN-101007786-B 2[(3-phenyl) acrylketony]-3-methylquinoxaline chemical synthesis method UNIV HUAZHONG AGRICULTURAL 2010-07-28 — — CN claimed
CN-100537548-C Method of producing 3- methyl group - quinoline -2- carboxylic acid UNIV JIANGNAN (CN) 2009-09-09 — — CN claimed
US-7344656-B2 Storing a composition in an alcoholic gel TRUOX, INC. (US) 2008-03-18 — — US claimed
CN-101007786-A 2[(3-phenyl) acrylketony]-3-methylquinoxaline chemical synthesis method UNIV HUAZHONG AGRICULTURAL (CN) 2007-08-01 — — CN claimed
WO-2005013913-A2 PEROXYGEN CONTAINING PARTICLE IN AN ALCOHOL CONTAINING GEL MATERIALS TECHNOLOGY LABORATORIES, INC. (US) 2005-02-17 — — WO claimed
US-20050032660-A1 Storing a composition in an alcoholic gel TRUOX, INC. 2005-02-10 — — US claimed
US-4228151-A QUINOXALINE DIOXIDE L'OREAL (FR) 1980-10-14 — — US claimed
EP-4658656-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES Beone Medicines I GmbH (CH) 2025-12-10 — — EP disclosed
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES BEONE MEDICINES I GMBH (CH) 2025-11-13 — — US disclosed
US-4228151-A QUINOXALINE DIOXIDE L'OREAL (FR) 1980-10-14 — — US disclosed
US-4001017-A REDOX CATALYSTS, DIAZINES, ELECTRON DONORS CIBA-GEIGY AG (CH) 1977-01-04 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346597-A1 CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES DGKG, DGKA, DGKK MAPT 4168/4885ALDH1A1 4075/4885SMN1; SMN2 4584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.