SCHEMBL3701892

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14099196	0.87	MAPT (0.62)	MAPTALDH1A1SMN1; SMN2MAPK1CASP1
	SCHEMBL634399	0.83	ALDH1A1 (0.72)	TDP1MAPTALDH1A1SMN1; SMN2KDM4E
	SCHEMBL6992814	0.83	TDP1 (0.56)	TDP1MAPTALDH1A1SMN1; SMN2PABPC1
	Hydrochloric Acid SCHEMBL10562751	0.82	ALDH1A1 (0.69)	TDP1MAPTALDH1A1SMN1; SMN2KDM4E
	SCHEMBL3574871	0.82	TDP1 (0.54)	TDP1MAPTALDH1A1SMN1; SMN2KDM4E
	SCHEMBL4111048	0.81	KDM4E (0.50)	TDP1MAPTALDH1A1SMN1; SMN2MAPK1
	SCHEMBL27985020	0.81	TDP1 (0.48)	TDP1MAPTALDH1A1SMN1; SMN2MAPK1
	SCHEMBL17616107	0.81	KMT2A (0.47)	TDP1MAPTALDH1A1KDM4EKMT2A
	SCHEMBL4833903	0.79	MAPT (0.54)	MAPTALDH1A1SMN1; SMN2MAPK1CASP1
	SCHEMBL47270	0.79	MAPT (0.54)	MAPTALDH1A1SMN1; SMN2MAPK1CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.