SCHEMBL4834045

SCHEMBL4834045

O=C1C2C(C(=O)N1OS(=O)(=O)c1cccc3cccnc13)C1C(=O)N(OS(=O)(=O)c3cccc4cccnc34)C(=O)C21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 2/20 0.51
▸ CA1 P00915 1/20 0.51
▸ CA2 P00918 1/20 0.51
▸ CA9 Q16790 1/20 0.51
▸ TSHR P16473 1/20 0.49
▸ GFER P55789 1/20 0.49
▸ MAPT P10636 3/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ SMN1; SMN2 Q16637 1/20 0.49
▸ L3MBTL1 Q9Y468 1/20 0.48
▸ GAA P10253 3/20 0.48
▸ KDM4E B2RXH2 3/20 0.48
▸ APOBEC3G Q9HC16 2/20 0.48
▸ NPSR1 Q6W5P4 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.45
▸ METAP2 P50579 1/20 0.45
▸ METAP1 P53582 1/20 0.45
▸ POLB P06746 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4835127 0.88 TSHR (0.52) MAPK1CA1CA2CA9TSHR
SCHEMBL4827240 0.78 TSHR (0.37) MAPK1CA1CA2CA9TSHR
SCHEMBL4834111 0.77 CA1 (0.46) CA1CA2CA9TSHRMAPT
SCHEMBL4826403 0.77 TSHR (0.34) MAPK1CA1CA2CA9TSHR
SCHEMBL3829853 0.75 ALDH1A1 (0.55) MAPK1CA1CA2CA9TSHR
SCHEMBL13290860 0.74 MAPK1 (0.62) MAPK1CA1CA2CA9TSHR
SCHEMBL3823208 0.71 FABP1 (0.41) MAPK1CA1CA2CA9TSHR
SCHEMBL4834531 0.70 KDM4E (0.44) MAPK1CA2MAPTMEN1KMT2A
SCHEMBL7180056 0.70 MAPK1 (0.70) MAPK1CA1CA2CA9TSHR
SCHEMBL27592567 0.70 MAPK1 (0.70) MAPK1CA1CA2CA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 — — US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 — — US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 MAPK1 2128/4885CA1 603/4885CA2 1249/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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