SCHEMBL4826403

SCHEMBL4826403

O=C1C2C=CC3C(C4C(=O)N(OS(=O)(=O)c5cccc6cccnc56)C(=O)C24)C1C(OS(=O)(=O)c1cccc2cccnc12)[N+]3=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSHR P16473 1/20 0.34
▸ GFER P55789 1/20 0.34
▸ MAPT P10636 3/20 0.33
▸ MAPK1 P28482 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ CA9 Q16790 1/20 0.33
▸ FABP1 P07148 2/20 0.33
▸ L3MBTL1 Q9Y468 1/20 0.33
▸ ALDH1A1 P00352 4/20 0.33
▸ ALOX15 P16050 1/20 0.33
▸ GAA P10253 3/20 0.32
▸ KDM4E B2RXH2 2/20 0.32
▸ APOBEC3G Q9HC16 2/20 0.32
▸ TP53 P04637 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4834045 0.77 MAPK1 (0.51) TSHRGFERMAPTMAPK1MEN1
SCHEMBL4835754 0.74 KDM4E (0.35) MAPTALDH1A1KDM4E
SCHEMBL4827240 0.74 TSHR (0.37) TSHRGFERMAPTMAPK1MEN1
SCHEMBL4837171 0.71 — —
SCHEMBL4835127 0.69 TSHR (0.52) TSHRGFERMAPTMAPK1MEN1
SCHEMBL4837041 0.65 TSHR (0.35) TSHRGFERMAPTMAPK1MEN1
SCHEMBL3829853 0.61 ALDH1A1 (0.55) TSHRGFERMAPTMAPK1MEN1
SCHEMBL13290860 0.58 MAPK1 (0.62) TSHRGFERMAPTMAPK1MEN1
SCHEMBL4834111 0.58 CA1 (0.46) TSHRMAPTMEN1KMT2ACA1
SCHEMBL28541594 0.56 KMT2A (0.59) MAPTMAPK1MEN1KMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 — — US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 — — US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 TSHR 3884/4885GFER 1306/4885MAPT 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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