SCHEMBL483419

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL484113	0.84	F2 (0.38)	ALDH1A1KDM4EPTGS2MAPTCA12
	SCHEMBL13189594	0.82	ALDH1A1 (0.38)	ALDH1A1KDM4ELMNAHPGDMCOLN3
	SCHEMBL485360	0.81	MAPT (0.43)	ALDH1A1KDM4ELMNAHPGDMAPT
	SCHEMBL13189823	0.78	KDM4E (0.40)	ALDH1A1KDM4ELMNAHPGDPTGS2
	SCHEMBL12403512	0.76	PTGS2 (0.35)	ALDH1A1KDM4ELMNAPTGS2MAPT
	SCHEMBL12323532	0.76	F2 (0.43)	ALDH1A1KDM4EPTGS2MAPTCA9
	SCHEMBL483857	0.74	APP (0.39)	ALDH1A1KDM4ELMNAHPGDMCOLN3
	SCHEMBL13189600	0.73	CA12 (0.53)	MAPTCA12CA1CA9MEN1
	SCHEMBL12324100	0.73	CA12 (0.48)	MAPTCA12CA1CA9
	SCHEMBL484168	0.73	AR (0.47)	ALDH1A1KDM4ELMNAHPGDPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.