SCHEMBL485360

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL484168	0.82	AR (0.47)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL483419	0.81	ALDH1A1 (0.39)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL2164493	0.76	NCF1 (0.59)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL483949	0.76	MAPT (0.39)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL12403530	0.76	MAPT (0.39)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL12324227	0.76	APP (0.47)	MAPTAPP
	SCHEMBL13164748	0.75	RAB9A (0.43)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL12403514	0.72	NPC1 (0.46)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL12324091	0.72	NPC1 (0.46)	MAPTNPC1RAB9AKDM4EALDH1A1
	SCHEMBL13164747	0.69	MAPT (0.61)	MAPTAPPMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.