SCHEMBL484168

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2164493	0.83	NCF1 (0.59)	ARNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL485360	0.82	MAPT (0.43)	ARNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL6602159	0.80	NCF1 (0.61)	NCF1CYP1A2POLBLMNAL3MBTL1
	SCHEMBL6741522	0.80	POLB (0.40)	NPC1RAB9AALDH1A1MEN1KMT2A
	SCHEMBL13164748	0.74	RAB9A (0.43)	ARNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL21974285	0.72	KDM4E (0.51)	ARNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL12970409	0.72	RAB9A (0.50)	ARNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL8739602	0.72	AR (0.58)	ARNPC1RAB9AKDM4ESMN1; SMN2
	SCHEMBL12324101	0.72	POLB (0.45)	SMN1; SMN2MAPTTRPV1DGAT1CYP1A2
	SCHEMBL15249330	0.69	AR (0.51)	ARNPC1RAB9AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.