SCHEMBL4834253

SCHEMBL4834253

O=C1c2ccc(Oc3ccc4c(c3)C(=O)N(OS(=O)(=O)c3cc(Cl)ccc3Cl)C4=O)cc2C(=O)N1OS(=O)(=O)c1cc(Cl)ccc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.43
MEN1 O00255 4/20 0.43
VDR P11473 2/20 0.43
ALDH1A1 P00352 8/20 0.42
KDM4E B2RXH2 8/20 0.42
MAPT P10636 5/20 0.42
HPGD P15428 4/20 0.42
F2 P00734 3/20 0.42
HTT P42858 3/20 0.42
LMNA P02545 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
XBP1 P17861 2/20 0.40
POLB P06746 2/20 0.40
MAPK1 P28482 2/20 0.40
ALOX15 P16050 1/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALPL P05186 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3823911 0.87 KMT2A (0.45) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL3825331 0.83 KDM4E (0.58) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL4827206 0.80 HSD11B1 (0.39) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL3830348 0.74 ALDH1A1 (0.74) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL3824621 0.74 KDM4E (0.71) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL4829791 0.74 ALDH1A1 (0.47) KMT2AALDH1A1KDM4EMAPTHPGD
SCHEMBL3824184 0.73 KMT2A (0.48) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL3823934 0.73 POLB (0.49) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL3825755 0.73 KDM4E (0.46) KMT2AMEN1VDRALDH1A1KDM4E
SCHEMBL3829861 0.73 KMT2A (0.68) KMT2AMEN1VDRALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7374857-B2 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2008-05-20 US disclosed
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition WAKO PURE CHEMICAL INDUSTRIES LTD. (JP) 2005-02-17 US disclosed
EP-1449833-A1 BISIMIDE COMPOUND, ACID GENERATOR AND RESIST COMPOSITION EACH CONTAINING THE SAME, AND METHOD OF FORMING PATTERN FROM THE COMPOSITION Wako Pure Chemical Industries, Ltd. (JP) 2004-08-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050038261-A1 Bismide compound, acid generator and resist composition each containing the same, and method of forming pattern from the composition ASIC1, GAR1, RER1 KMT2A 1016/4885MEN1 211/4885VDR 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.