SCHEMBL483464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13127444	0.82	CASP3 (0.41)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL3305147	0.80	PIK3CD (0.42)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL12402796	0.76	GRM5 (0.48)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL12403502	0.76	GRM5 (0.48)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL13394608	0.71	APP (0.40)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL23480172	0.71	NPC1 (0.52)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL1011755	0.70	TXNRD1 (0.51)	TDP1MAPTALDH1A1HSD17B10NAMPT
	SCHEMBL29517954	0.70	TXNRD1 (0.51)	TDP1MAPTALDH1A1HSD17B10NAMPT
	SCHEMBL6477863	0.70	ALDH1A1 (0.45)	RAB9AKDM4ENPC1HKDC1TDP1
	SCHEMBL31106335	0.69	TXNRD1 (0.50)	TDP1MAPTALDH1A1HSD17B10NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.