Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.36 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.36 |
| ▸ | TGM2 | P21980 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29517954 | 0.83 | TXNRD1 (0.51) | TXNRD1TXNRD3TXNRD2ALDH1A1CYP3A4 | |
| SCHEMBL1011755 | 0.83 | TXNRD1 (0.51) | TXNRD1TXNRD3TXNRD2ALDH1A1CYP3A4 | |
| SCHEMBL483464 | 0.82 | RAB9A (0.35) | ALDH1A1TDP1FFAR1HSD17B10NAMPT | |
| SCHEMBL31106335 | 0.82 | TXNRD1 (0.50) | TXNRD1TXNRD3TXNRD2ALDH1A1CYP3A4 | |
| SCHEMBL13165180 | 0.81 | MAPT (0.45) | CASP3SENP8SENP7SENP6TXNRD1 | |
| SCHEMBL13394608 | 0.77 | APP (0.40) | ALDH1A1CYP3A4TDP1HTTSMN1; SMN2 | |
| SCHEMBL393608 | 0.77 | ALDH1A1 (0.53) | TXNRD1TXNRD3TXNRD2ALDH1A1CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL9639241 | 0.75 | ALDH1A1 (0.51) | TXNRD1TXNRD3TXNRD2ALDH1A1CYP3A4 | |
| SCHEMBL14664048 | 0.74 | CASP3 (0.63) | CASP3SENP8SENP7SENP6ALDH1A1 | |
| Benzo[D]Thiazole SCHEMBL2404928 | 0.74 | ALDH1A1 (0.58) | TXNRD1TXNRD3TXNRD2ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100239496-A1 | Imaging agents for detecting neurological disorders | SIEMENS MEDICAL SOLUTIONS USA, INC. (US) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100239496-A1 | Imaging agents for detecting neurological disorders | MAPT, APP, PSEN1 | CASP3 3618/4885SENP8 1387/4885SENP7 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.