Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849261 | 0.97 | LMNA (0.32) | LMNATSHRNFKB1PMP22 | |
| SCHEMBL175939 | 0.89 | CES2 (0.48) | TSHRHSD17B10 | |
| SCHEMBL5824425 | 0.89 | CES2 (0.48) | TSHRHSD17B10 | |
| SCHEMBL9478004 | 0.89 | CES2 (0.48) | TSHRHSD17B10 | |
| SCHEMBL5824929 | 0.89 | CES2 (0.48) | TSHRHSD17B10 | |
| SCHEMBL31673513 | 0.86 | — | — | |
| SCHEMBL5825929 | 0.83 | — | — | |
| SCHEMBL5825346 | 0.77 | — | — | |
| SCHEMBL11860907 | 0.76 | LMNA (0.36) | LMNATSHRNFKB1PMP22HDAC3 | |
| SCHEMBL31261311 | 0.76 | LMNA (0.36) | LMNATSHRNFKB1PMP22HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 159 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3643735-B1 | PHOTOCHROMIC POLYROTAXANE COMPOUND, AND CURABLE COMPOSITION CONTAINING SAID PHOTOCHROMIC POLYROTAXANE COMPOUND | TOKUYAMA CORP (JP) | 2024-07-31 | — | — | EP | disclosed |
| EP-3779531-B1 | PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME | TOKUYAMA CORP (JP) | 2024-03-20 | — | — | EP | disclosed |
| US-11767467-B2 | Photochromic compound and curable composition containing said photochromic compound | TOKUYAMA CORPORATION (JP) | 2023-09-26 | — | — | US | disclosed |
| US-20230120549-A1 | Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same | PPG INDUSTRIES OHIO, INC. | 2023-04-20 | — | — | US | disclosed |
| EP-3653615-B1 | CHROMENE COMPOUND, CURABLE COMPOSITION COMPRISING SAME, AND OPTICAL ARTICLE COMPRISING CURED PRODUCT FORMED OF CURABLE COMPOSITION | TOKUYAMA CORP (JP) | 2023-03-01 | — | — | EP | disclosed |
| US-11472912-B2 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2022-10-18 | — | — | US | disclosed |
| US-11401276-B2 | Chromene compound, curable composition comprising the compound, and optical article including a cured body of the curable composition | TOKUYAMA CORPORATION (JP) | 2022-08-02 | — | — | US | disclosed |
| US-20220162486-A1 | PHOTOCHROMIC OPTICAL ARTICLE AND METHOD FOR MANUFACTURING SAME | TOKUYAMA CORPORATION (JP) | 2022-05-26 | — | — | US | disclosed |
| US-20220119581-A1 | Aircraft Windows | PPG INDUSTRIES, INC. | 2022-04-21 | — | — | US | disclosed |
| US-11248083-B2 | Aircraft windows | PPG INDUSTRIES OHIO, INC. (US) | 2022-02-15 | — | — | US | disclosed |
| EP-0665219-A1 | Polythiol, process for producing same, sulfur-containing urethane-base resin prepared from the polythiol, process for producing the resin, and lens | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5389708-A | Polymerizing polyisocyanate or polyisothiocyanate with polyol or polythiol in presence of thiophosphoric or dithiophosphoric acid ester | MITSUI TOATSU CHEMICALS, INC. (JP) | 1995-02-14 | — | — | US | disclosed |
| EP-0630927-A2 | Optical urethane resin | Takeda Chemical Industries, Ltd. (JP) | 1994-12-28 | — | — | EP | disclosed |
| US-5352758-A | Polythiourethane formed by reaction of specific mercaptan with polyisocyanate or polyisothiocyanate | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1994-10-04 | — | — | US | disclosed |
| EP-0351073-B1 | Lens comprising a resin having a large refractive index and process for preparing the lens | MITSUI TOATSU CHEMICALS (JP) | 1994-09-21 | — | — | EP | disclosed |
| US-5283312-A | Colorless, transparent, high refractive index, heat resistance, low dispersion; polythiourethanes | MITSUI TOATSU CHEMICALS, INC. (JP) | 1994-02-01 | — | — | US | disclosed |
| EP-0553801-A1 | Use of sulfur-containing acid phosphoric ester as internal release agent | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-08-04 | — | — | EP | disclosed |
| EP-0528590-A1 | Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-02-24 | — | — | EP | disclosed |
| US-5084545-A | Polythiourethanes for impact strength, lightweight lenses | MITSUI TOATSU CHEMICALS, INC. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0351073-A2 | Lens comprising a resin having a large refractive index and process for preparing the lens | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11401276-B2 | Chromene compound, curable composition comprising the compound, and optical article including a cured body of the curable composition | INCENP, SMCHD1, ILK | LMNA 296/4885TSHR 1571/4885NFKB1 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.