Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | NOD1 | Q9Y239 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511128 | 1.00 | KMT2A (0.52) | KMT2ANOD1POLBSLC6A5MEN1 | |
| SCHEMBL28000179 | 0.96 | KMT2A (0.51) | KMT2ANOD1POLBSLC6A5MEN1 | |
| SCHEMBL4968856 | 0.93 | TSHR (0.51) | KMT2ANOD1POLBMEN1FAAH | |
| SCHEMBL9762126 | 0.88 | KMT2A (0.64) | KMT2ANOD1POLBMEN1FAAH | |
| SCHEMBL155009 | 0.88 | KMT2A (0.64) | KMT2ANOD1POLBMEN1FAAH | |
| SCHEMBL155010 | 0.88 | NOD1 (0.55) | KMT2ANOD1POLBSLC6A5MEN1 | |
| SCHEMBL9762130 | 0.88 | NOD1 (0.55) | KMT2ANOD1POLBSLC6A5MEN1 | |
| SCHEMBL9762120 | 0.88 | KMT2A (0.64) | KMT2ANOD1POLBMEN1FAAH | |
| SCHEMBL21495973 | 0.88 | NOD1 (0.55) | KMT2ANOD1POLBSLC6A5MEN1 | |
| SCHEMBL21838299 | 0.88 | NOD1 (0.55) | KMT2ANOD1POLBSLC6A5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1213011-B1 | Cosmetic material comprising branched silicone compounds | SHINETSU CHEMICAL CO (JP) | 2016-02-17 | — | — | EP | disclosed |
| US-9090755-B2 | Organopolysiloxane polymer, pasty composition, and cosmetic preparation containing the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-8828410-B2 | Pasty composition and cosmetics containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-8808675-B2 | Organopolysiloxane hair treatment agent and hair cosmetic containing the treatment agent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-08-19 | — | — | US | disclosed |
| EP-1618872-B1 | ORGANOPOLYSILOXANE HAIR TREATMENT AGENT AND HAIR COSMETIC CONTAINING THE TREATMENT AGENT | SHINETSU CHEMICAL CO (JP) | 2013-07-24 | — | — | EP | disclosed |
| EP-1992656-B9 | Novel Organopolysiloxanpolymer, Pasty Composition, and Cosmetic Preparation Containing the Composition | SHINETSU CHEMICAL CO (JP) | 2012-09-26 | — | — | EP | disclosed |
| EP-1426027-B1 | COMPOSITION AND COSMETIC PREPARATION CONTAINING THE SAME | SHINETSU CHEMICAL CO (JP) | 2012-09-05 | — | — | EP | disclosed |
| EP-1935924-B1 | Pasty composition, and cosmetic preparation containing the same | SHINETSU CHEMICAL CO (JP) | 2012-06-06 | — | — | EP | disclosed |
| EP-1992656-B1 | Novel Organopolysiloxanpolymer, Pasty Composition, and Cosmetic Preparation Containing the Composition | SHINETSU CHEMICAL CO (JP) | 2012-05-23 | — | — | EP | disclosed |
| EP-1550687-B1 | NOVEL ORGANOPOLYSILOXANE POLYMER, PASTY COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE COMPOSITION | SHINETSU CHEMICAL CO (JP) | 2012-05-23 | — | — | EP | disclosed |
| EP-1213011-A1 | Cosmetic material comprising branched silicone compounds | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6399081-B1 | SILICONE RESIN POWDER WITH TABULAR SHAPE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-06-04 | — | — | US | disclosed |
| US-20020058053-A1 | COSMETIC MATERIAL COMPRISING ORGANOPOLYSILOXANE-GRAFTED SILICONE COMPOUND | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| US-20010018044-A1 | Novel silicone compound, a powder surface-treated with this compound, and a makeup containing this powder | SHIN-ETSU CHEMICAL CO., LTD. OF (JP) | 2001-08-30 | — | — | US | disclosed |
| US-20010014312-A1 | Novel silicon compound, and a makeup containing this compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-16 | — | — | US | disclosed |
| EP-1122276-A2 | A novel silicone compound and a makeup containing this compound | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-1122277-A2 | A novel silicone compound, a powder surface-treated with this compound, and makeup containing this powder | Shin-Etsu Chemical Co., Ltd. (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-1072627-A2 | Silicone compound and cosmetic materials containing the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-01-31 | — | — | EP | disclosed |
| EP-1065234-A2 | Silicones for powder treatment powders having surface treated with said silicones, and cosmetic materials containing said powders | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-01-03 | — | — | EP | disclosed |
| EP-1062944-A1 | Cosmetic material | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2000-12-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010014312-A1 | Novel silicon compound, and a makeup containing this compound | LOXL1, SAAL1, ACVRL1 | KMT2A 2312/4885NOD1 4248/4885POLB 2138/4885 |
| US-20020058053-A1 | COSMETIC MATERIAL COMPRISING ORGANOPOLYSILOXANE-GRAFTED SILICONE COMPOUND | H1-0, H1-2, H1-3 | KMT2A 2730/4885NOD1 4537/4885POLB 813/4885 |
| US-20010018044-A1 | Novel silicone compound, a powder surface-treated with this compound, and a makeup containing this powder | SCARB1, SAAL1, HBS1L | KMT2A 1953/4885NOD1 3775/4885POLB 2010/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.