Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPOR | P19235 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.37 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4775430 | 0.83 | ALDH1A1 (0.44) | BCHEALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL2104742 | 0.76 | CENPE (0.46) | ALOX5PTGS1PTGS2L3MBTL1MEN1 | |
| SCHEMBL5569175 | 0.73 | ALOX5 (0.47) | ALOX5LTA4H | |
| SCHEMBL5570351 | 0.73 | BCHE (0.55) | BCHEMEN1KMT2A | |
| SCHEMBL7608457 | 0.73 | BCHE (0.41) | BCHEALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL4718727 | 0.72 | CENPE (0.42) | ALOX5PTGS1PTGS2L3MBTL1MEN1 | |
| SCHEMBL7606237 | 0.71 | NPC1 (0.39) | L3MBTL1 | |
| SCHEMBL4775432 | 0.71 | ALDH1A1 (0.46) | BCHEL3MBTL1MEN1KMT2A | |
| SCHEMBL7608227 | 0.71 | PTGS1 (0.40) | BCHEALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL4718071 | 0.70 | CENPE (0.49) | ALOX5PTGS1PTGS2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1942732-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056143-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |