Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778783 | 0.78 | LTA4H (0.56) | LTA4H | |
| SCHEMBL5570351 | 0.76 | BCHE (0.55) | — | |
| SCHEMBL8329893 | 0.76 | ACP1 (0.52) | PPARARXRARXRBMRGPRX4 | |
| SCHEMBL2617475 | 0.74 | HDAC3 (0.51) | PPARGPPARAMAOBRXRARXRB | |
| SCHEMBL29609086 | 0.74 | EPHX1 (0.66) | PPARGPPARAEPHX1 | |
| SCHEMBL28622582 | 0.74 | EPHX1 (0.66) | PPARGPPARAEPHX1 | |
| SCHEMBL5569179 | 0.73 | LTA4H (0.55) | LTA4H | |
| SCHEMBL4837138 | 0.73 | BCHE (0.42) | ALOX5LTA4H | |
| SCHEMBL11445970 | 0.73 | MAOB (0.60) | ALOX5FFAR1PPARGPPARAMAOB | |
| SCHEMBL4775430 | 0.72 | ALDH1A1 (0.44) | ALOX5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | CYTOKINETICS, INCORPORATED | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219192-A1 | Certain chemical entities, compositions, and methods | KIF5B, KIF2C, PLK1 | ALOX5 4662/4885FFAR1 4743/4885PPARG 2756/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.