Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4837267 | 1.00 | GLO1 (0.50) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL8944831 | 0.88 | ALDH1A1 (0.48) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL14186860 | 0.88 | ALDH1A1 (0.48) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL12600412 | 0.86 | ALDH1A1 (0.46) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL5496037 | 0.82 | ALDH1A1 (0.53) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL28166960 | 0.80 | ALDH1A1 (0.50) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL4456094 | 0.80 | ALDH1A1 (0.50) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL26663491 | 0.80 | ALDH1A1 (0.50) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| SCHEMBL15962409 | 0.80 | ALDH1A1 (0.50) | GLO1ALDH1A1LMNAHSD17B10EGLN1 | |
| Ethyl Pyruvate SCHEMBL28039252 | 0.79 | GLO1 (0.58) | GLO1ALDH1A1LMNAHSD17B10EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170298055-A1 | sGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC. (US) | 2017-10-19 | — | — | US | disclosed |
| US-20150050592-A1 | TONER FOR ELECTROSTATIC CHARGE IMAGE DEVELOPMENT, METHOD OF MANUFACTURING THE SAME, AND IMAGE FORMING METHOD | Konica Minolta, Inc. (JP) | 2015-02-19 | — | — | US | disclosed |
| US-20120231385-A1 | ELECTROPHOTOGRAPHIC TONER SET | KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) | 2012-09-13 | — | — | US | disclosed |
| US-7420087-B2 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-09-02 | — | — | US | disclosed |
| US-7420087-B2 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-09-02 | — | — | US | disclosed |
| US-7420087-B2 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.) (FR) | 2008-09-02 | — | — | US | disclosed |
| US-20060205817-A1 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | UNIVERSITE LOUIS PASTEUR (FR) | 2006-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060205817-A1 | Method for preparing 4-hydroxyisoleucine diastereoisomers and enantiomers and derivatives thereof | CYP4F11, CYP2F1, CYP2S1 | GLO1 533/4885ALDH1A1 893/4885LMNA 989/4885 |
| US-20170298055-A1 | sGC STIMULATORS | GUCY1B1, GUCY1A1, PRKG2 | GLO1 1590/4885ALDH1A1 1921/4885LMNA 3591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.